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1、E-RLPOpoly(ethylacrylate-co-methylmethacrylate-co-triammonioethylmethacrylatechloride)PARAMETERUNITVALUEREFERENCESGENERALCommonnamepoly(ethylacrylatecomethylmethacrylatecotriammonioethylmethacrylatechloride)IUPACnamepoly(ethylacrylatecomethylmethacrylatecotriammonioethylmethacrylatechloride)AcronymE
2、RLPOCASnumber33434241(RL&RS)SYNTHESISMonomerratio(EA:MM:TAM)1:2:0.2Massaveragemolecularweight,dalton,g/32,000150,000Mmol,amuwPolydispersity,M/M1.5wnCOMMERCIALPOLYMERSSomemanufacturersEvonicTradenamesEudragitRS&RLPHYSICALPROPERTIESDensityat20oCgcm-30.8160.836ColormilkywhitetolightyellowRefractiveinde
3、x,20oC1,3801.385Odorcharacteristic,faintFilmformingtemperature(min)oC4045GlasstransitiontemperatureoC5070WEATHERSTABILITYSpectralsensitivitynm196210deOliveira,HP;Tavares,GF;Nogueiras,C;Rieymont,J,Int.J.Pharmaceutics,5561,2009.PROCESSINGTypicalprocessingmethodsspraying,dryingProcessingtemperatureoC90
4、100(dryingair)ApplicationsMUPS,timecontrolledreleasecoating,pHindependentAbdul,S;Chandewar,AV;Jaiswal,SB,J.ControlledRelease,147,216,2010.Outstandingpropertieslowpermeability,pHindependentswelling,pHindependentdrugrelease,highlyflexibleANALYSISFTIR(wavenumber-assignment)cm-1/estergroups11501190,12401
5、270;C=O173;CH1385,1450,1475,2950300086HANDBOOKOFPOLYMERS/Copyrights2012;ChemTecPublishingEAApoly(ethylene-co-acrylicacid)PARAMETERUNITVALUEREFERENCESGENERALCommonnamepoly(ethylenecoacrylicacid)ACSname2propenoicacid,polymerwithetheneAcronymEAACASnumber9010779SYNTHESISMonomer(s)structureOH2CCH2H2CCHCO
6、HMonomer(s)CASnumber(s)74851;79107Monomer(s)molecularweight(s)dalton,g/28.05;72.06mol,amuAcrylicacidcontent%538Aromacity%010ofaromaticprotonsTemperatureofpolymerizationoC240300PressureofpolymerizationMPa200300Numberaveragemoleculardalton,g/28031,000weight,Mmol,amunMassaveragemolecularweight,dalton,g
7、/45086,000Mmol,amuwPolydispersity,M/M1.13.97McAlduff,M;Reven,L,Macromolwnecules,38,374553,2005.STRUCTURECrystallinity%837Zhang,J;Chen,S;Su,J;Shi,X;Jin,J;Wang,X;Xu,Z,J.Therm.Anal.Calorim.,97,95967,2009
