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1、HANDBOOKOFGENERICDRUGDEVELOPMENTANDADEVELOPMENTHANDBOOKofPharmaceuticalGenericDevelopmentControlledReleaseOralTabletsPharmaceuticalDrugDevelopmentVOLUMEI0-PartTwoANDADevelopment-SolidCROralDosageFormsANDADEVELOPMENTHANDBOOKOFGENERICDRUGDEVELOPMENTANDADEVELOPMENTHANDBOOKOFGENERICDRUGDEVELOPMEN
2、TANDADEVELOPMENTHandbookofPharmaceuticalGenericLocumInternationalPublishersDevelopmentoralCRPartTWOANDADEVELOPMENTTabletsNeitherthisbooknoranypartmaybereproducedortransmittedinanyformorbyanymeans,electronicormechanical,includingphotocopying,microfilmingandrecording,orbyanyinformationstoragean
3、dretrievalsystem,withoutthepermissionofthepublishers.Copyright©1995-2000LocumPublishingHouseInc.LocumInternationalPublishersAllRightsReserved.ALocumHousePublicationHANDBOOKOFGENERICDRUGDEVELOPMENTANDADEVELOPMENTHANDBOOKOFGENERICDRUGDEVELOPMENTANDADEVELOPMENTHPGDSeriesCRTabletsOral-PartII.Firs
4、tInternationalEdition-01.FirstpublishedanddistributedinUnitedKingdom,EuropeanUnion,RSA,IsraelandJapaninJanuary1995byLocumInternationalPublishingHouse(Houston,Israel,SouthAfrica).SecondInternationalEdition-02.PublishedanddistributedinUnitedKingdom,UnitedStates,EuropeanUnion,Israel,AsiaandJapan
5、inJune1998byLocumInternationalPublishingHouse(Houston,Israel,SouthAfrica).ThirdInternationalEdition-03.PublishedinMarch2000anddistributedinUnitedKingdom,UnitedStates,EuropeanUnion,Israel,AsiaandJapanbyLocumInternationalPublishingHouse(Houston,Israel,SouthAfrica).Copyright©1995-2000HandbookofP
6、harmaceuticalGenericDevelopmentTextCopyright©1994-HandbookofPharmaceuticalGenericDevelopmentIllustrationcopyright©1994-HandbookofPharmaceuticalGenericDevelopmentLocumInternationalPublishingHousePOBox874,50GiladStreetKochavYair44864Israel.Allrightreserved.ISSNSeries07938772-PartOneISSNSeries07
7、938780-PartTwoGENERALDrugDevelopmentSeriesISSN07937601GENERALGenericSeriesISSN07937407GENERALGenerice-SeriesISSN07937792-ElectronicDisc/CDROMVersionGENERALISSNDrugDevelopmente-Series0793761X-ElectronicDiscVersionGeneralISSNSeriesnumber0793779