有机药物在碳糊电极上的吸附伏安法分析

《有机药物在碳糊电极上的吸附伏安法分析》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、易兰花：有机药物在碳糊电极上的吸附伏安法研究AbstractAnodicadsorptivestrippingvoltammetricdeterminationsofastemizole,rifampicini,ciprofloxacinandnorfloxacinatcarbonpasteelectrode（CPE）weredescribed,Theirelectrodereactionmechanismswereinvestigated.Theproposedmethodswereappliedtodeterminepracticesampleswith

2、satisfiedresults.Thepaperconsistsofthreechapters.Inthefirstchapter,ahighlyselectiveandrapidnewanodicadsorptivevoltammetricmethodwasdevelopedforthedeterminationoftraceamountofastemizoleatCPEinthecurrentpaper.TheastemizolewasadsorbedonthesurfaceofaCPEin0.40mol/LHAc-NaAcbuffersolution

3、(pH4.6)yieldingoneoxidationpeakat0.84V(vs.SCE)whenscanningfrom0.0to1.0V.Thelinearrelationshipbetweenthepeakcurrentandastemizoleconcentration-9-7isintherangeof2.0×10~1.0×10mol/L(90saccummulation).-10Thecorrelationcoefficientis0.9980.Itsdetectionlimitis6.0×10mol/L(S/N=3)fora90saccumm

4、ulation.Therelativestandard-7deviationis3.6﹪for15successivedeterminationsof1.0×10mol/Lastemizoleonasameelectrodesurface.Theelectrodereactionmechanismofastemizolewasinvestigated.Theproposedmethodwasappliedtodetermineastemizoleintheastemizoletabletandtheresultswereingoodagreementwith

5、referencevaluesofthespectrophometricdetermination.Inthesecondchapter,rifampiciniwasadsorbedonthesurfaceofaCPEin0.40mol/LNaAc-HAcbuffersolution(pH4.9)yieldingoneoxidationpeakat0.86V(vs.SCE)whenscanningfrom0.0to1.0V.Thelinearrelationshipbetweenthepeakcurrentand-8-6rifampiciniconcentr

6、ationisintherangeof1.0×10~2.0×10易兰花：有机药物在碳糊电极上的吸附伏安法研究mol/L(90saccummulation).Thecorrelationcoefficientis0.9986.-9Itsdetectionlimitis3.0×10mol/L(S/N=3)fora120saccummulation.TheRSDof3.3﹪isobtainedfor15determinations-7ofrifampiciniat4.0×10mol/LlevelonasameCPEsurface.Theelectrodeproce

7、ssesofrifampiciniwereinvestigated.Theproposedmethodwasappliedtodirectdeterminetracerifampiciniintheurinesamplesingoodagreementwithreferencevaluesofthespectrophometricdetermination.Inthethirdchapter,ciprofloxacinandnorfloxacinwereadsorbedonthesurfaceofCPEin0.40mol/LNH4Ac-HAcbufferso

8、lution,yieldingoneoxidatio