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1、《癌症》ChineseJournalofCancer,2007,26(7):673-678673·快速报道·局限性残留、复发鼻咽癌的鼻内镜进路救援性外科治疗陈明远1,21,231,21,2,郭翔,文卫平,华贻军,郭灵,李宁炜1,21,21,21,2,陈秋燕,孙蕊,洪明晃SalvageSurgicalOperationviaEndoscopicTransnasalApproachforLocalPersistentorRecurrentNasopharyngealCarcinoma1,21,231,21,2CHENMing-Yuan,GUOXiang,WENWei-Ping,
2、HUAYi-Jun,GUOLing,1,21,21,21,2LINing-Wei,CHENQiu-Yan,SUNRui,HONGMing-Huang[ABSTRACT]BACKGROUND&OBJECTIVE:Somepatientswithlocalpersistentorrecurrentnasopharyngealcarcinoma(NPC)couldachieve1.华南肿瘤学国家重点实验室,long-termsurvivalafterre-irradiation,buttheirradiation-relatedcomplications广东广州510060are
3、severe.Salvagesurgicaloperationhassimilar,evenbetter,curative2.中山大学肿瘤防治中心effect,withnoirradiationinjury,butconventionalsurgicalapproachesmay鼻咽科,leadtoseriousdamage,andunclearviewofoperationfieldistheobstacle广东广州510060forenblocexcisionofthetumor.Thisstudywastoexploreanewsalvage3.中山大学附属第一医院s
4、urgicaloperationviamini-invasiveendoscopictransnasalapproachfor耳鼻咽喉科医院,recurrentNPC.METHODS:Endoscopicnasopharyngectomyviamini-invasive广东广州510060endoscopictransnasalapproachwasperformedin25patientswithlocalpersistentorrecurrentNPCafterradiotherapybetweenSep.2004andJan.1.StateKeyLaboratoryo
5、f2007inCancerCenterofSunYat-senUniversity.LocalcontrolconditionsandOncologyinSouthChina,complicationswereassessed.RESULTS:AllpatientsreceivedsuccessfulGuangzhou,Guangdong,510060,radicalresectionviaendoscopictransnasalapproach;only1hadpositiveP.R.Chinasurgicalmargin.Noonereceivedpostoperati
6、veradiotherapy.Duringfollow-2.DepartmentofNasopharyngealupof3-31months(median,13months),1patienthadlocalpersistence,3Carcinoma,hadlocalrecurrence,butnonehaddistantmetastasisordeath.The1-yearCancerCenter,overallsurvivalratewas100%;the1-yearrecurrence-freesurvivalratewasSunYat-senUniversity,
7、86.0%.Notrismus,dysphagia,dysphonia,othersurgicalcomplications,Guangzhou,Guangdong,510060,andperioperativedeathoccurred.CONCLUSIONS:SalvagesurgicaloperationP.R.Chinaviaendoscopictransnasalapproachcanexposethewholenasopharynxand3.DepartmentofOtolaryngology,thes