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1、NilsArvold,HMSIVGillianLieberman,MDJuly2006ImagingProstateCancer:ImagingProstateCancer:Diagnosis,Staging,andRadiotherapyDiagnosis,Staging,andRadiotherapyNilsNilsArvoldArvold,HarvardMedicalSchoolYearIV,HarvardMedicalSchoolYearIVGillianLieberman,MDGillianLieberman,MDNilsArvo
2、ld,HMSIVGillianLieberman,MDOverviewOverviewProstate––FunctionandAnatomyProstateCancer––RoleofImaging––EpidemiologyandPresentation––Diagnosis:TransrectalTransrectalU/Sbiopsy––Staging:EndorectalEndorectalcoilMRI+/--bonescan,CTRadiotherapy––RelianceonImaging––Evolution:Conven
3、tionalto3Dto4D––ExternalBeamRT3DConformalRTImagingusingCTMRSpectroscopyandIntensity-ModulatedRT4DImage-guidedRTwithElectronicPortalImaging––BrachytherapyTRUSvsMRguidancePost-implantationCTNilsArvold,HMSIVGillianLieberman,MDReviewReviewProstateisa4x3x2cmexocrineglandencircl
4、ingtheurethrabetweenthebladderandurogenitalurogenitaldiaphragmPrincipalfunction=produceproteinsthatformthebulkofseminalfluidAtejaculation,prostateandseminalvesiclesecretionsturnintoagel-likestructureentrappingthespermatozoa.Theejaculatedspermatozoabecomeprogressivelymotile
5、asthegeldissolves.http://www.mansgland.comSecretorySecretoryfunctionfunctionismediatedbycholinergicinnervationinnervation(pelvicandhypogastrichypogastricnerves);contractilecontractilefunctionfunctionismediatedbyalpha-adrenergicreceptorsofthefibromuscularfibromuscularstroma
6、http://www.malecare.com/services1.htmNilsArvold,HMSIVGillianLieberman,MDBasicAnatomyProstateBaseApexTheprostateissurroundedbya2-3mmcapsuleNetterFH.AtlasofHumanAnatomy,3rded.Saunders2002.NilsArvold,HMSIVGillianLieberman,MDZonalAnatomyZonalAnatomyProstateterritoriesarenowdes
7、cribedintermsofzonesinsteadoflobesAxialSagittalCoronal-TransitionZone=surroundsprostaticurethra“CentralGland”-CentralZone=posteriortourethra,locatedsuperiorly-PeripheralZone=mostlyposteriortourethra,locatedinferiorlyandlaterallyGoluboffETetal.RadicalProstatectomyfortheTrea
8、tmentofProstateCancer.InAtlasofNovellineetal.Squire'sFundamentalsofRadiology:SixthEdition
