中晚期食管癌支架置入术后并发症的相关分析研究及其与粒子支架的应用比较

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1、授予单位代码10089学号或申请号13042HebeiMedicalUniversity硕士学位论文在职科学学位中晚期食管癌支架置入术后并发症的相关分析研究及其与粒子支架的应用比较学位申请人：戴守方导师：李顺宗主任医师专业：影像医学与核医学二级学院：第四医院2015年3月河北医科大学学位论文使用授权及知识产权归禺承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数

2、据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。研究生签醒章：達4二鮮隨#盖章乂/七年j月5日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名导师签章：；y/f年t月u日目录中文摘要·············································································1英文摘要·······

3、······································································3研究论文中晚期食管癌支架置入术后并发症的相关分析研究及其与粒子支架的应用比较前言·············································································7材料与方法····································································7结果··················

4、···························································9附图·············································································11附表·············································································18讨论···························································

5、··················20结论·············································································25参考文献·······································································26综述食管癌支架治疗的并发症研究现状···································29致谢·················································

6、··································39个人简历·············································································40中晚期食管癌覆膜支架置入术后并发症的相关分析研究及其与粒子支架的应用比较摘要目的：食管支架置入术作为晚期食管癌姑息性治疗的主要方法，存在的主要问题为各种并发症。本研究分析各种并发症产生的因素，为并发症的预防提供指导。方法：随访我院2011年1月-2013年12月经病理证实为食管癌而在我科成功进行支架治疗的患者。随访主要以电话和

7、门诊复查方式进行。随访内容包括患者身体健康情况、后续治疗情况、疼痛、出血、支架移位或脱落、食管穿孔、反流性食管炎、再狭窄及死亡时间等。对于有吞咽困难的患者进行上消化道造影，检验是否存在再次狭窄；对于出现反复咳嗽、发热或呼吸困难等症状的患者行CT检查或碘比醇上消化道造影以除外穿孔；死亡患者了解具体死亡时间。分析普通覆膜支架病人疼痛、出血、移位、穿孔、反流性食管炎及再狭窄的发生率，进行统计学分析，比较各种发病因素下并发症出现的统计学差异。比较普通覆膜支架和粒子支架两组病人以上各种并发症的发生率及统计学差异。比较两组患者的再狭窄率和生存期，分析其统计学差异。统计学方

8、法应用SPSS17.0统计学软件，生存