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1、BranchocclusivediseaseClinicalandmagneticresonanceangiographyfindingsS.Ryoo,MDABSTRACTJ.H.Park,MDBackground:WeevaluatedtheclinicoradiologiccharacteristicsofpatientswithbranchocclusiveS.J.Kim,MDdisease(BOD)–typeintracranialatheroscleroticstroke(ICAS)com
2、paredwiththoseofpatientsG.-M.Kim,MD,PhDwithnon-BOD–typeICASorwithsmallarterydisease(SAD).C.-S.Chung,MD,PhDMethods:Weanalyzed201consecutivepatientswithacuteinfarctswithinthemiddlecerebralK.H.Lee,MD,PhDartery(MCA)distributionbutnodemonstrablecarotidorcar
3、diacembolismsources.AccordingtoJ.S.Kim,MD,PhDthediffusion-weightedimaging(DWI)distributionandthepresenceofipsilateralMCAstenosis,ofO.Y.Bang,MD,PhDanydegree,onmagneticresonanceangiography(3-TMRI),wedividedpatientsinto3groups:1)BOD:subcorticalinfarctswit
4、hMCAstenosis(n46);2)non-BOD:infarctsbeyondthesubcorti-calareawithMCAstenosis(n52);and3)SAD(n103).Wecomparedriskfactors,degreeofCorrespondence&reprintrequeststoDr.Bang:stenosesanddistribution,andradiologicfeaturesofmicroangiopathy(leukoaraiosisandcer
5、ebralnmboy@unitel.co.krmicrobleeds)amongthegroups.Results:Riskfactorprofilesweresimilaramongthegroups,exceptthathypertensionandcurrentsmokingweremoreprevalentinthenon-BODthanintheBODgroup(p0.032and0.045).TherelevantMCAhadmoresevereandfocalstenosisinth
6、enon-BODthanintheBODgroup(stenosisof70%;76.9%vs28.3%;p0.001),butthedegreeofnonrelevantstenosiswassimilaracrossthegroups.Althoughclinicalfeatures,DWIlesionpatterns,andmicroangiopathyfindingsweresimilarbetweentheBODandSADgroups,nonrelevantstenosiswasmo
7、reprevalentintheBODthanintheSADgroup(p0.01).Conclusions:BODisprevalent(47%ofICAS)andsharescommoncharacteristicswithnon-BOD–typeICAS,althoughitsclinicoradiologicfeaturesmayresemblethoseofSAD.Themorphologiccharacteristicsofstenosisandriskfactorsmayassoc
8、iatewithastrokephenotypeinpatients®withICAS.Neurology2012;78:888–896GLOSSARYBODbranchocclusivedisease;CMBcerebralmicrobleed;DWIdiffusion-weightedimaging;FLAIRfluid-attenuatedinversionrecovery;ICASintracranialatheroscleroticstroke;L
