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1、StatisticalMethodsforBiostatisticsandRelatedFieldsWolfgangHärdle·YuichiMoriPhilippeVieuStatisticalMethodsforBiostatisticsandRelatedFieldsWith91Figuresand57Tables123ProfessorWolfgangHärdleCASE-CenterforAppliedStatisticsandEconomicsInstituteforStatisticsandEconometricsSch
2、oolofBusinessandEconomicsHumboldtUniversitätzuBerlinSpandauerStr.110178Berlinhaerdle@wiwi.hu-berlin.deProfessorYuichiMoriDepartmentofSocio-informationOkayamaUniversityofSciences1-lRidai-cho700-0005Okayamamori@soci.ous.ac.jpProfessorPhilippeVieuLaboratoiredeStatistiqueet
3、ProbabilitésUniversitéPaulSabatier118routedeNarbonne31062ToulouseCedexvieu@cict.frLibraryofCongressControlNumber:2006934207ISBN-13978-3-540-32690-8SpringerBerlinHeidelbergNewYorkThisworkissubjecttocopyright.Allrightsarereserved,whetherthewholeorpartofthematerialisconcer
4、ned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broad-casting,reproductiononmicrofilmorinanyotherway,andstorageindatabanks.DuplicationofthispublicationorpartsthereofispermittedonlyundertheprovisionsoftheGermanCopyrightLawofSeptember9,19
5、65,initscurrentversion,andpermissionforusemustalwaysbeobtainedfromSpringer.ViolationsareliabletoprosecutionundertheGermanCopyrightLaw.SpringerispartofSpringerScience+BusinessMediaspringer.com©Springer-VerlagBerlinHeidelberg2007Theuseofgeneraldescriptivenames,registeredn
6、ames,trademarks,etc.inthispublicationdoesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevantprotectivelawsandregulationsandthereforefreeforgeneraluse.Production:LE-TEXJelonek,Schmidt&V¨ocklerGbR,LeipzigCover-design:ErichKirchner,Heidelber
7、gSPIN11681021154/3100YL-543210Printedonacid-freepaperPrefaceBiostatisticsisoneofthescientificfieldsforwhichthedevelopmentsduringthelastdecadesofthe20thcenturyhavebeenthemostimportant.Bio-statisticsisapluri-disciplinaryareacombiningstatisticsandbiology,butalsoagronomics,me
8、dicineorhealthsciences.Itneedsagoodknowledgeofthemathematicalbackgroundinherentinstatisticalmethodology,inorde
