北沙参在大鼠体内代谢物的鉴定与北沙参—麦冬配伍的药物动力学研究

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1、授予单位代码10089学号或申请号20122680HebeiMedicalUniversity硕士学位论文科学学位北沙参在大鼠体内代谢物的鉴定与北沙参-麦冬配伍的药物动力学研究研究生：王双导师：王巧教授专业：药物分析学2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文是在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容相关的论文，第一署名单位为河北医科大学，试验材料、原始数据、

2、申报的专利等知识产权均归河北医科大学所有。否则，承担相应的法律责任。研究生签名：王双导师签章:.年河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注等内容外，文中不包含其他人已发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：王双导师签章:对年^月访曰目录中文摘要·················································································1英文

3、摘要·················································································5英文缩写···············································································11研究论文北沙参在大鼠体内代谢物的鉴定与北沙参-麦冬配伍的药物动力学研究·····························································

4、·····13引言···············································································13第一部分北沙参在大鼠体内的吸收组分与其代谢物的鉴定···············14前言···············································································14材料与方法·············································

5、·························15结果···············································································18附图···············································································26附表······································································

6、·········37讨论···············································································43小结···············································································44参考文献·········································································44第二部分北沙参-麦

7、冬配伍的药物动力学研究·······························45前言···············································································45材料与方法······································································46结果···························································

8、····················51附图···············································································54附表······································