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1、前路“杂交式”减压融合治疗多节段颈椎病Anteriorhybriddecompressionwithfusionfortreatingmultilevelcervicalspondylosis作者姓名:郝朋元领域(方向):外科学指导教师:顾锐副教授类别:临床医学硕士答辩日期:2015年6月1日中文摘要目的:回顾性研究以评价前路杂交式(ACCF联合ACDF)融合的手术方案治疗多节段颈椎病的临床疗效。方法:对自2012年3月至2014年6月11例多节段病变的颈椎病患者采用前路杂交式(主要病变节段椎体
2、次全切、次要节段单纯间盘摘除、钛笼植骨、Cage撑开、钢板固定)融合手术方案治疗,分析患者年龄、手术时间、术中出血量、病变节段、融合节段Cobb角、比较术前术后JOA评分,计算改善率,影像学资料衡量术后内固定状况与愈合情况,以及有无严重并发症发生。结果:随访时间8至24个月,平均随访时间15个月,术后JOA评分较术前提高,改善率优良,平均手术时间,术中平均出血量;采用前路杂交式融合的手术方案术后未出现C5神经根刺激征、硬膜囊破裂、神经功能恶化等严重并发症,随访过程中无植骨块延期愈合、内固定物下沉
3、等并发症发生;至末次随访,未出现椎体坍塌、内固定失败等严重并发症,1例在末次随访中出现邻近节段退变,但未出现脊髓压迫症状及不适主诉,随访过程中复查X线片、CT证实植骨愈合良好。结论:前路杂交式(ACCF联合ACDF)融合手术方案是治疗多节段颈椎I病的一种可供选择的较理想手术方案。关键词:杂交式;融合;三个阶段;前路;颈椎病。IIAbstractObjective:Toevaluateretrospectivelyclinicalcurativeeffectofanteriorhybriddeco
4、mpressionwithfusion(ACCFcombinedwithACDF)intreatmentofmultilevelcervicalspondylosisMethod:FromFebruary,2012tonow,11casesinmultilevelcervicalspondylosisreceivedtreatmentofanteriorhybriddecompressionwithfusion,analyzingtheageofpatients,operationtime,pe
5、ri-operativebleeding,theCobbangleoffusion,comparingpre-andpostoperativeJOAscore,calculatingimprovementrate,appraisingtheconditionsofinternalfixationandbonehealing,andseriouscomplicationsornotbyimages.Result:8to22monthsfollow-uptime,15monthsonaverage,
6、JOAscoreandimprovementrateisraisedinvaryingdegree,averageoperationtime,averagebloodlossduringoperationandaveragehospitalizationtimewerelow;therewerenocomplicationincludingdelayedbonegraftunion,sinkingofinternalfixationandsoonbyanteriorhybriddecompres
7、sionwithfusion;attheendoffollow-up,therewerenoseriouscomplication,suchasvertebralcollapsephenomenon,fixationIIIfailureandsoon.Duringthefollow-up,theexaminationofX-ray,CTdemonstratedbonegraftgrowedwell.Conclusion:Theoperationplanofanteriorhybriddecomp
8、ressionwithfusionisanidealoperationschemeforthetreatmentofmultilevelcervicalspondylosis,withmoreadvantages.Keywords:hybrid;fusion;threelevel;anterior;cervicalspondylosis;IV目录第1章引言.......................................................................