急性有机磷农药中毒患者血清il-18水平的检测及临床意义

《急性有机磷农药中毒患者血清il-18水平的检测及临床意义》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码１００８９学号或申请号１３１０２？巧＾（ｉ钟Ａ這ＨｅｂｅｉＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ硕±学位论文在职科学学位急性有机磯农药中毒患者血清ＩＬ－１８水平的检测及临床意义学位申请人：刘晓婷导师；石汉文教授王维展教授专业：急诊區学二级学院：第二医院２０１５年１０月河化医科大学学位论文使用授权及知识产权归属承诘本学位论文在导师。（或指导小组）的指导下，由本人独立完成本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本擎位论文进行交流、公开和使用。凡

2、发表一与学位论文主要内容相关的论文署名为单位河北医科大学，，第试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。。否则，承担相应法律责任＇—一＂．京＾：＞Ｖ葦：：研究生签名晰＾奇：刮今导师签章级学院领导盖４捂寡＾；。年月Ｖ義暑Ｖ河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果。本论文由本人，指导教师对此进行了审定独立撰写，文责自负。研巧生签名：；导师签章少戶／（年＾月日目录中文摘要···

3、···········································································1英文摘要··············································································3研究论文急性有机磷农药中毒患者血清IL-18水平的检测及临床意义前言··············································································5资料与方法·············

4、························································6结果··············································································7附图··············································································9附表·····································································

5、·········12讨论··············································································14结论··············································································20参考文献········································································20综述脓毒症与IL-18··························

6、···································23致谢····················································································36个人简历··············································································37中文摘要急性有机磷农药中毒患者血清IL-18水平的检测及临床意义摘要目的：探讨观察白细胞介素-18（interleukin-18，IL-18）水平值变化在急性有机

7、磷农药中毒（Acuteorganophosphatepoisoning，AOPP）患者中的临床作用。本研究通过动态检测IL-18的含量，观察其与血清C反应蛋白（CRP）、谷丙转氨酶（ALT）含量、病情严重程度之间的关系，旨在探索IL-18水平值与AOPP患者病情严重程度的相关性，有助于早期病情评估及预后。方法：选择2013年1月至2015年1月在衡水市哈励逊国际和平医院急诊就诊患者，完善病例资料采集，选取96例AOPP患者，其中中度AOPP患者70例，重度AOPP患者26例，所有患者均符合国家卫生部第八版内科学教材