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1、GeneRegulationFifthEditionGeneRegulationAeukaryoticperspectiveFifthEditionDavidSLatchmanMasterofBirkbeck,UniversityofLondonProfessorofGenetics,BirkbeckandDean,InstituteofChildHealth,UniversityCollegeLondonPublishedby:Taylor&FrancisGroupInUS:270MadisonAvenueNewYork,NY10016InUK:4ParkSquare,MiltonPa
2、rkAbingdon,OX144RNThiseditionpublishedintheTaylor&Francise-Library,2007.“TopurchaseyourowncopyofthisoranyofTaylor&FrancisorRoutledge’scollectionofthousandsofeBookspleasegotowww.eBookstore.tandf.co.uk.”©2005byTaylor&FrancisGroupFirstpublished1990;Fiftheditionpublished2005ISBN0-203-01633-5Mastere-b
3、ookISBNISBN:0-4153-6510-4(PrintEdition)Thisbookcontainsinformationobtainedfromauthenticandhighlyregardedsources.Reprintedmaterialisquotedwithpermission,andsourcesareindicated.Awidevarietyofreferencesarelisted.Reasonableeffortshavebeenmadetopublishreliabledataandinformation,buttheauthorandthepubli
4、shercannotassumeresponsibilityforthevalidityofallmaterialsorfortheconsequencesoftheiruse.Allrightsreserved.Nopartofthisbookmaybereprinted,reproduced,transmitted,orutilizedinanyformbyanyelectronic,mechanical,orothermeans,nowknownorhereafterinvented,includingphotocopying,microfilming,andrecording,or
5、inanyinformationstorageorretrievalsystem,withoutwrittenpermissionfromthepublishers.AcatalogrecordforthisbookisavailablefromtheBritishLibrary.LibraryofCongressCataloging-in-PublicationDataLatchman,DavidS.Generegulation:aeukaryoticperspective/DavisS.Latchman.--5thed.p.cm.Includesbibliographicalrefe
6、rencesandindex.ISBN0-415-36510-41.Geneticregulation.2.Geneexpression.3.Eukaryoticcells.4.Genetictranscription.I.Title.QH450.2.L372006572.8'65--dc222005009966Editor:ElizabethOwenEditorialAssistant:ChrisDixonProductionEditor:KarinHendersonTaylor&FrancisGroupistheAcademicDivisionofT&FInformaplc.Visi
7、tourwebsiteathttp://www.garlandscience.comTomymotherandinmemoryofmyfatherCONTENTSAbbreviationsxiPrefacetothefiftheditionxiiPrefacetothefirsteditionxiiiPrefacetothesecondeditionxivPrefacetothethirdeditionxvPrefacetothefou