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ID:34835253
大小:3.92 MB
页数:68页
时间:2019-03-12
《探析胆甾型液晶用于体温精密测量的研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、天津大学硕士学位论文胆甾型液晶用于体温精密测量的研究姓名:张磊申请学位级别:硕士专业:化学工艺指导教师:唐韶坤20070601摘要体温的变化直接反映着身体的健康状况,因此测量体温是诊断疾病最常用的方法。而液晶体温卡的种种优点使其在医学测温领域中占据了显著的地位并备受瞩目。本文根据胆甾型液晶热致变色精密示温的特点,一方面研究并确定适于在人体体温测量范围内灵敏变色从而可精确测温的液晶物系,另一方面探讨并确定液晶微囊化工艺技术的适宜参数和条件,为以后液晶体温卡工业化生产奠定基础。本文首先通过实验确定了在人体体温范围内精密测温的胆甾型
2、混合液晶体系为胆甾烯基油烯基碳酸酯:75.7%(训%)、胆甾烯基氯:17.7%(叭%)、胆甾烯基月桂酸酯:6.60%(州%)。进而开发了通过加入添加剂改变混合液晶清亮点温度的方法,实验确定2撑添加剂为适宜添加剂,同时获得了在人体体温范围内精密变色的液晶组成与清亮变色点对应数据。各清亮点实验值与计算值绝对误差3、清亮点之间变化不规律、重复性、可视性差的缺点,增大了液晶体系在医学测温领域的应用范围。另外对液晶微囊化工艺进行了研究。实验考察了乳化温度、乳化速度、乳化时间、囊材与芯材质量比、成囊温度、搅拌速度、成囊pH值和稀释水量等因素对复凝聚法制备液晶徼囊工艺的影响,得到适宜的工艺条件:成囊温度65℃,稀释水量200ml/g(稀释水量/芯材质量),搅拌速度400转/分钟,成囊pH值4,囊材与芯材质量比2:l,乳化温度55℃,乳化速度2000转/分钟,乳化时间l小时。包埋率最高接近60%,获得的液晶微胶囊在稳定性上有了显著提高,与未经过包囊4、的液晶相比,抗氧化、抗晶析效果明显增强。关键词:液晶:胆甾型液晶;液晶体温卡;微囊化:液晶微胶囊ABSTRACTThechangingofbodytemperaturemayreflectone’Shealthyconditiondirectly,SObodytemperaturemeasurementisacommonmethodofdiagnosing.Theclinicalliquidcrystalthermometerisanew,cleanandgreenproduct,whichispresentlyconside5、redasoneofthemostpowerfultechnologyinthefieldofclinicaltemperaturemeasurementandhasbeenpaidmuchattention.Accordingtothethermochromismofcholestericliquidcrystalforshowingthebodytemperature,liquidcrystalclinicalthermometerhavebeenstudiedinthispaper.Ononehand,thesystem6、ofliquidcrystalmixtureinapplicationtoclinicalthermometerwasexploredandontheotherhandthetechnicalconditionsofencapsulatingliquidcrystalmaterialswereobtained.Theresearchworkwillestablishafoundationforindustrializedproductionofclinicalliquidcrystalthermometer.First,cho7、lestericliquidcrystalsystemwhichwasappliedtomeasuretemperatureintherangeofbodytemperaturewasestablishedinthethesis.Thatischolesteryloleylcarbonate:75.7%(wt%);cholestcrylchloride:17.7%C毗%);cholesteryllaurate:6.60%(叭%).Furthermoreamethodthatclearingpointoftemperatureo8、fliquidcrystalmixturewouldbechangedbyaddinganadditiveint0themixturehasbeendeveloped.Theresultsshow2捍additiveisfeasibletoapplyingtopreparec
3、清亮点之间变化不规律、重复性、可视性差的缺点,增大了液晶体系在医学测温领域的应用范围。另外对液晶微囊化工艺进行了研究。实验考察了乳化温度、乳化速度、乳化时间、囊材与芯材质量比、成囊温度、搅拌速度、成囊pH值和稀释水量等因素对复凝聚法制备液晶徼囊工艺的影响,得到适宜的工艺条件:成囊温度65℃,稀释水量200ml/g(稀释水量/芯材质量),搅拌速度400转/分钟,成囊pH值4,囊材与芯材质量比2:l,乳化温度55℃,乳化速度2000转/分钟,乳化时间l小时。包埋率最高接近60%,获得的液晶微胶囊在稳定性上有了显著提高,与未经过包囊
4、的液晶相比,抗氧化、抗晶析效果明显增强。关键词:液晶:胆甾型液晶;液晶体温卡;微囊化:液晶微胶囊ABSTRACTThechangingofbodytemperaturemayreflectone’Shealthyconditiondirectly,SObodytemperaturemeasurementisacommonmethodofdiagnosing.Theclinicalliquidcrystalthermometerisanew,cleanandgreenproduct,whichispresentlyconside
5、redasoneofthemostpowerfultechnologyinthefieldofclinicaltemperaturemeasurementandhasbeenpaidmuchattention.Accordingtothethermochromismofcholestericliquidcrystalforshowingthebodytemperature,liquidcrystalclinicalthermometerhavebeenstudiedinthispaper.Ononehand,thesystem
6、ofliquidcrystalmixtureinapplicationtoclinicalthermometerwasexploredandontheotherhandthetechnicalconditionsofencapsulatingliquidcrystalmaterialswereobtained.Theresearchworkwillestablishafoundationforindustrializedproductionofclinicalliquidcrystalthermometer.First,cho
7、lestericliquidcrystalsystemwhichwasappliedtomeasuretemperatureintherangeofbodytemperaturewasestablishedinthethesis.Thatischolesteryloleylcarbonate:75.7%(wt%);cholestcrylchloride:17.7%C毗%);cholesteryllaurate:6.60%(叭%).Furthermoreamethodthatclearingpointoftemperatureo
8、fliquidcrystalmixturewouldbechangedbyaddinganadditiveint0themixturehasbeendeveloped.Theresultsshow2捍additiveisfeasibletoapplyingtopreparec
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