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1、ThispageintentionallyleftblankNumericalandStatisticalMethodsforBioengineeringThisistheÞrstMATLAB-basednumericalmethodstextbookforbioengineersthatuniquelyintegratesmodelingconceptswithstatisticalanalysis,whilemaintainingafocusonenablingtheusertoreporttheerrororuncertaintyintheirr
2、esult.Betweentraditionalnumericalmethodtopicsoflinearmodelingconcepts,non-linearrootÞnding,andnumericalintegration,chaptersonhypothesistesting,dataregression,andprobabilityareinterweaved.Auniquefeatureofthebookistheinclusionofexamplesfromclinicaltrialsandbioinformatics,whicharen
3、otfoundinothernumericalmethodstextbooksforengineers.Withawealthofbiomedicalengineeringexamples,casestudiesontopicalbiomedicalresearch,andtheinclu-sionofendofchapterproblems,thisisaperfectcoretextforaone-semesterundergraduatecourse.MichaelR.KingisanAssociateProfessorofBiomedicalE
4、ngineeringatCornellUniversity.Heisanexpertonthereceptor-mediatedadhesionofcirculatingcells,andhasdevelopednewcomputationalandinvitromodelstostudythefunctionofleukocytes,platelets,stem,andcancercellsunderßow.Hehasco-authoredtwobooksandreceivednumerousawards,includingthe2008ICNMMO
5、utstandingResearcherAwardfromtheAmericanSocietyofMechanicalEngineers,andreceivedthe2009OutstandingContributionforaPublicationintheInternationalJournalClinicalChemistry.NipaA.ModyiscurrentlyapostdoctoralresearchassociateatCornellUniversityintheDepartmentofBiomedicalEngineering.Sh
6、ereceivedherPh.D.inChemicalEngineeringfromtheUniversityofRochesterin2008andhasreceivedanumberofawardsincludingaRuthL.KirschsteinNationalResearchServiceAward(NRSA)fromtheNIHin2005andtheEdwardPeckCurtisAwardforExcellenceinTeachingfromUniversityofRochesterin2004.CAMBRIDGETEXTSINBIO
7、MEDICALENGINEERINGSeriesEditorsW.MARKSALTZMAN,YaleUniversitySHUCHIEN,UniversityofCalifornia,SanDiegoSeriesAdvisorsWILLIAMHENDEE,MedicalCollegeofWisconsinROGERKAMM,MassachusettsInstituteofTechnologyROBERTMALKIN,DukeUniversityALISONNOBLE,OxfordUniversityBERNHARDPALSSON,Universityo
8、fCalifornia,SanDiegoNICHOLASPEPPAS,Universityof