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1、TheLupusBook:AGuideforPatientsandTheirFamilies,ThirdEditionDANIELJ.WALLACEOXFORDUNIVERSITYPRESSTheLupusBookThispageintentionallyleftblankTheLupusBookAGuideforPatientsandTheirFamiliesThirdEditionDANIELJ.WALLACE,MDCedars-SinaiMedicalCenterClinicalProfe
2、ssorofMedicineDavidGeffenSchoolofMedicineatUCLALosAngeles,California120051OxfordUniversityPress,Inc.,publishesworksthatfurtherOxfordUniversity’sobjectiveofexcellenceinresearch,scholarship,andeducation.OxfordNewYorkAucklandCapeTownDaresSalaamHongKongK
3、arachiKualaLumpurMadridMelbourneMexicoCityNairobiNewDelhiShanghaiTaipeiTorontoWithofficesinArgentinaAustriaBrazilChileCzechRepublicFranceGreeceGuatemalaHungaryItalyJapanPolandPortugalSingaporeSouthKoreaSwitzerlandThailandTurkeyUkraineVietnamCopyright
4、1995,2000,2005byOxfordUniversityPress,Inc.PublishedbyOxfordUniversityPress,Inc.198MadisonAvenue,NewYork,NewYork10016www.oup.comOxfordisaregisteredtrademarkofOxfordUniversityPressAllrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrie
5、valsystem,ortransmitted,inanyformorbyanymeans,electronic,mechanical,photocopying,recording,orotherwise,withoutthepriorpermissionofOxfordUniversityPress.LibraryofCongressCataloging-in-PublicationDataWallace,DanielJ.(DanielJeffrey),1949–Thelupusbook:ag
6、uideforpatientsandtheirfamilies/DanielJ.Wallace.—3rded.p.cm.Includesbibliographicalreferencesandindex.ISBN-13:978-0-19-518181-4ISBN-10:0-19-518181-61.Systemiclupuserythematosus—Popularworks.I.TitleRC924.5.L85W352005616.7'72—dc222004057638135798642Pri
7、ntedintheUnitedStatesofAmericaonacid-freepaperContentsForewordtotheFirstEditionbyHenriettaAladjem,viiPrefacetotheThirdEdition,ixPrefacetotheFirstEdition,xiPartIIntroductionandDefinitions1.WhyWriteaBookonLupus?32.WhatIsLupus?53.TheHistoryofLupus,94.Who
8、GetsLupus?11PartIIInflammationandImmunity5.TheBody’sProtectionPlan,176.TheEnemyIsOurCells,26PartIIIWhatCausesLupus?7.TheGeneticConnection,398.EnvironmentalVillains,439.DrugsThatMayCauseLupusorProduceFlareups,49PartIVWhereandHowCantheBodyBeAffectedbyLu