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1、MODELSOFCELLULARREGULATIONThispageintentionallyleftblankModelsofCellularRegulationBaltazarD.AgudaAvnerFriedmanMathematicalBiosciencesInstituteTheOhioStateUniversity13GreatClarendonStreet,OxfordOX26DPOxfordUniversityPressisadepartmentoftheUniversityofOxf
2、ord.ItfurtherstheUniversity’sobjectiveofexcellenceinresearch,scholarship,andeducationbypublishingworldwideinOxfordNewYorkAucklandCapeTownDaresSalaamHongKongKarachiKualaLumpurMadridMelbourneMexicoCityNairobiNewDelhiShanghaiTaipeiTorontoWithofficesinArgenti
3、naAustriaBrazilChileCzechRepublicFranceGreeceGuatemalaHungaryItalyJapanPolandPortugalSingaporeSouthKoreaSwitzerlandThailandTurkeyUkraineVietnamOxfordisaregisteredtrademarkofOxfordUniversityPressintheUKandincertainothercountriesPublishedintheUnitedStates
4、byOxfordUniversityPressInc.,NewYorkcBaltazarD.AgudaandAvnerFriedman,2008ThemoralrightsoftheauthorhavebeenassertedDatabaserightOxfordUniversityPress(maker)FirstPublished2008Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsyste
5、m,ortransmitted,inanyformorbyanymeans,withoutthepriorpermissioninwritingofOxfordUniversityPress,orasexpresslypermittedbylaw,orundertermsagreedwiththeappropriatereprographicsrightsorganization.Enquiriesconcerningreproductionoutsidethescopeoftheaboveshoul
6、dbesenttotheRightsDepartment,OxfordUniversityPress,attheaddressaboveYoumustnotcirculatethisbookinanyotherbindingorcoverandyoumustimposethesameconditiononanyacquirerBritishLibraryCataloguinginPublicationDataDataavailableLibraryofCongressCataloginginPubli
7、cationDataDataavailableTypesetbyNewgenImagingSystems(P)Ltd.,Chennai,IndiaPrintedinGreatBritainonacid-freepaperbyBiddlesLtd.,KingsLynn,NorfolkISBN978–0–19–857091–2(pbk)13579108642PrefaceTherehasbeenalotofexcitementsurroundingthescienceofbiologyinrecentye
8、ars.Thehumangenomeofthreebillionlettershasbeensequenced,ashavethegenomesofthousandsofotherorganisms.Withunprecedentedresolution,therushofomicstechnologiesisallowingustopeekintotheworldofgenes,biomolecules,andcells–andfloodinguswit
