经桡动脉介入治疗急性st段抬高型心肌梗死有效性与安全性的meta分析

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1、目录摘要⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．1ABSTP,ACI"···········-············································-························-·······2前言⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯·．4研究内容与方法⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．51．纳入与捧黼⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯51．1研究类型⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯”51．2研究对象⋯⋯⋯⋯

2、⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯··51．3：：I：：{IIl黼··········································································51．4结局指标·········································-································51．5捧除标准⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯··72．检索策略⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯73．：jj：1Ii僦···············

3、········································．．．．．．．．．．-．．．．．．．．．．．．74．．1ili：III渐·······················································．．．·．·．·．··．．．．．．．．．．．．85．统计分析⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯·⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯“8结果⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯·．9{【jiIi{沧·-··················································

4、········．．．-·．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．19小结⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．28jllI?i射···········-···························································．．．．．．．．．．．．．．．．．．．．．．．．29参考文献⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．30糙·-···························································

5、··········．．．．．．．．．．．．．．．．．．．．．．．．35攻读硕士学位期间发表的学位论文⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯。。42导师评阅表⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．43新疆医科大学硕士学位论文经桡动脉介入治疗急性ST段抬高型心肌梗死有效性及安全性的Meta分析研究生：卜国森导师：木胡牙提教授，主任医师摘要目的：系统评价经桡动脉介入治疗急性ST段抬高型心肌梗死(sTEMI)疗效及安全性。方法：计算机检索PubMed、EMbaSe、CBM、TlleCochraneLibrary(2014年第6期)、CNKI、VIP和

6、WanFallgData，查找经桡动脉途径介入治疗急性STEMI疗效及安全性的随机对照试验(RCT)，检索时限为2000年至2014年11月。由2位评价员按照纳入与排除标准独立筛选文献、提取资料和评价纳入研究的方法学质量后，采用RevMaIl5．2软件进行Meta分析。结果：最终纳入14个RCT，共计5212例患者。Me诅分析结果显示：①与对照组相比，经桡动脉途径组可以明显减少病死率[OR=0．54，95％U(0．40，0．74)产0．0001]，减少主要大出血发生率[OR．=0．50，95％U(0．34，0。74)，p=0．0008]，降低主要不良心脏事件(MA

7、CE)发生率[OR=0．65，95％U(0．50，0．83)，仁O．00063，减少穿刺部位并发症[OR=0．35，95％U(O．25，0．49)，P

8、格把握适应