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1、ThispageintentionallyleftblankNETWORKSINCELLBIOLOGYThescienceofcomplexbiologicalnetworksistransformingresearchinareasrangingfromevolutionarybiologytomedicine.Thisisthefirstbookonthesub-ject,providingacomprehensiveintroductiontocomplexnetworkscienceanditsbiolog
2、icalapplications.Withcontributionsfromkeyleadersinbothnetworktheoryandmoderncellbiology,thisbookdiscussesthenetworksciencethatisincreasinglyfoundationalforsystemsbiologyandforthequantitativeunderstandingoflivingsystems.Itsurveysstudiesinthequantitativestructu
3、reanddynamicsofgeneticregulatorynetworks,molecularnetworksunderlyingcellularmetabolism,andotherfunda-mentalbiologicalprocesses.Thebookbalancesempiricalstudiesandtheorytogiveaunifiedoverviewofthisinterdisciplinaryscience.Itisakeyintroductorytextforgraduatestude
4、ntsandresearchersinphysics,biologyandbiochemistry,andpresentsideasandtechniquesfromfieldsoutsidethereader’sownareaofspecialization.MARKBUCHANANisaphysicistandindependentauthor.HewritesamonthlycolumnforthejournalNaturePhysics.GUIDOCALDARELLIisAssociateProfessor
5、intheCentreforStatisticalMechanics,CNR-INFM,Rome,andcollaborateswiththeResearchCentre‘E.Fermi’,theLaboratoryLINKALABandtheLondonInstituteforMathematicalSciences.PAOLODELOSRIOSisaProfessorintheLaboratoryofStatisticalBiophysics,InstituteofTheoreticalPhysics,Eco
6、lePolytechniqueFederaledeLausanne(EPFL).FRANCESCORAOresearchesintheLaboratoiredeChimieBiophysiqueattheUniversityofStrasbourgandattheResearchCentre‘E.Fermi’,Rome.MICHELEVENDRUSCOLOisaReaderinTheoreticalChemicalBiologyintheDepartmentofChemistryattheUniversityof
7、Cambridge.NetworksinCellBiologyEditedbyM.BUCHANANG.CALDARELLICNR-INFMP.DELOSRIOSEcolePolytechniqueFederaledeLausanneF.RAOUniversityofStrasbourgM.VENDRUSCOLOUniversityofCambridgeCAMBRIDGEUNIVERSITYPRESSCambridge,NewYork,Melbourne,Madrid,CapeTown,Singapore,SãoP
8、aulo,Delhi,Dubai,TokyoCambridgeUniversityPressTheEdinburghBuilding,CambridgeCB28RU,UKPublishedintheUnitedStatesofAmericabyCambridgeUniversityPress,NewYorkwww.cambridge.orgInformationonthi