《分子遗传学》英文版试题集总览

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1、FinalexamofMolecularBiologyCourse(Spring2004)2)agenomicclone.3)acDNAclone.PARTI:DESCRIPTION(2pointseach)4)theprotein.Youranswershoulddescribewhateachitemisandhowitfunctions7.Achromatographymethodthatcanbeusedspecificallytopurifyinthecell.Diagrams,structureandsequenceinformation

2、shouldbeproteinsbasedontheirchargeis:includedinyouranswer,asnecessary.1)gelfiltrationchromatography.1.Yeastartificialchromosome2)ion-exchangechromatography.2.RNAinterference3)DNAaffinitychromatography.3.Proteomics4)antibodyaffinitychromatography.4.Shine-Dalgarnosequence8.Anonse

3、nsemutationisachangeintheDNAsequencethat5.Alternativesplicingresultsin:6.Ribozyme1)asmalldeletionorinsertion.7.-dependenttermination2)anaminoacidchangeintheproteinencodedbythegene.8.RNAediting3)aprematurestopcodon.9.DNAlesions4)alloftheabove.10.Proteintargeting5)noneoftheabove.

4、9.AproteincomplexinvolvedindegradationofproteinswithinthePARTII:MULTIPLECHOICES(1pointseach)cellisknownasthe:Selecttheonebestanswerforeachquestion.1)ubiquitin/proteasomesystem.2)molecularchaperone.1.Thecatalyticactivityforpeptidebondformation(thepeptidyl3)chaperonin.transferase

5、activity)islocatedinthe:4)ribosome.1)RNAofthelargeribosomalsubunit.5)Krebs/TCAcycle.2)leadersequenceofthemessengerRNA.10.___bindstotherepressorandturnonthetranscriptionofthe3)RNAofthesmallribosomalsubunit.structuralgenesintheLacoperon.4)proteinsofthesmallribosomalsubunit.1)cAMP

6、5)proteinsofthelargeribosomalsubunit.2)lactose2.Bidirectionalandsemi-conservativearetwotermsthatreferto:3)allolactose1)transcription.4)CRP2)translation.11.WhichofthefollowingRNAspeciesisinvolvedindegradation3)replication.ofthemRNAcontainingcomplementarysequence4)alloftheabove.1

7、)miRNA5)noneoftheabove.2)siRNA3.Thefactthatmostaminoacidsarespecifiedbymultiplecodons3)tRNAisknownas:4)5SRNA1)the“wobble”phenomenon.5)U3snRNA2)theuniversalityofthegeneticcode.12.Thegenomesequencingprojectsareconfirmingthetheorythat3)codonbias.genomesizeisdirectlyproportionaltot

8、henumberofgenes4)theanticodonhypothesis.containedwithi