Ubiquitin Chains - Degradation and Beyond (2015)

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1、SpringerThesesRecognizingOutstandingPh.D.ResearchArnabDeUbiquitinChains:DegradationandBeyondSpringerThesesRecognizingOutstandingPh.D.ResearchMoreinformationaboutthisseriesathttp://www.springer.com/series/8790AimsandScopeTheseriesSpringerThesesbringstogetheraselectionoftheverybestPh.D.the

2、sesfromaroundtheworldandacrossthephysicalsciences.Nominatedandendorsedbytworecognizedspecialists,eachpublishedvolumehasbeenselectedforitsscientificexcellenceandthehighimpactofitscontentsforthepertinentfieldofresearch.Forgreateraccessibilitytonon-specialists,thepublishedversionsincludeanext

3、endedintroduction,aswellasaforewordbythestudentssupervisorexplainingthespecialrelevanceoftheworkforthefield.Asawhole,theserieswillprovideavaluableresourcebothfornewcomerstotheresearchfieldsdescribed,andforotherscientistsseekingdetailedbackgroundinformationonspecialquestions.Finally,itprovi

4、desanaccrediteddocumentationofthevaluablecontributionsmadebytodaysyoungergenerationofscientists.ThesesareacceptedintotheseriesbyinvitednominationonlyandmustfulfillallofthefollowingcriteriaTheymustbewritteningoodEnglish.ThetopicshouldfallwithintheconfinesofChemistry,Physics,EarthSciences,En

5、gineeringandrelatedinterdisciplinaryfieldssuchasMaterials,Nanoscience,ChemicalEngineering,ComplexSystemsandBiophysics.Theworkreportedinthethesismustrepresentasignificantscientificadvance.Ifthethesisincludespreviouslypublishedmaterial,permissiontoreproducethismustbegainedfromtherespectivecop

6、yrightholder.Theymusthavebeenexaminedandpassedduringthe12monthspriortonomination.Eachthesisshouldincludeaforewordbythesupervisoroutliningthesignificanceofitscontent.Thethesesshouldhaveaclearlydefinedstructureincludinganintroductionaccessibletoscientistsnotexpertinthatparticularfield.ArnabDe

7、UbiquitinChains:DegradationandBeyondDoctoralThesisacceptedbyColumbiaUniversityNewYork,NYAuthorSupervisorDr.ArnabDeProf.SankarGhoshDepartmentofMicrobiologyandChair,SilversteinandHuttFamilyProfessorImmunologyofMicrobiologyandImmunologyColumbiaUniversityMedicalCenterDepartme