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ID:33386800
大小:4.73 MB
页数:42页
时间:2018-05-21
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1、TheEvolutionoftheSurgicalTreatmentofChronicPancreatitis汇报人:柴大海导师:刘杰专业:普外2021/7/121BACKGROUNDOperativeapproachestothetreatmentofchronicpancreatitishaveundergoneadramatictransformationoverthepastfewdecades.Theheadofthepancreashasbecomeuniversallyapprec
2、iatedasthenidusofchronicinflammation.Prospective,randomizedtrialshaverepeatedlyshownthesuperiorityofsurgicaltreatmentovermedicalapproachestomanagement2021/7/122INDICATIONSFORSURGERYPainDuctalhypertension:someanatomicchangesrelatedwithitsuchas:smallcys
3、ts、fociofacinarcellnecrosis、areasofacuteinflammationPeripancreaticsensorynervedamage:inflammatorydamage、neuron-specificproteinaseactivatedreceptor2activation、Cfibers(asubpopulationofsensoryneurons)containpeptideswhichcancauseinflammatorychanges2.Thecompli
4、cationsofchronicpancreatitis2021/7/123TreatmentThemedicaltreatmentofchronicpancreatitis-associatedpainusuallyfailssurgicaltreatmentofchronicpancreatitishasbeenshowntoeliminatepainandreturnpatientstoprediseaseemploymentandquality-of-lifestatus.2021/7/
5、124OperativeproceduresOperativeproceduresaboutchronicpancreatitishavehistoricallybeenclassifiedinto3categories:DecompressionofdiseasedandobstructedpancreaticductsDenervationofthepancreasResectionoftheproximal,distal,ortotalpancreas.Withinthepastfewyea
6、rs,however,acategoryofhybridprocedureshasbeenshowntobesafeandeffective.2021/7/125DECOMPRESSIONPROCEDURESRemovecalculifromWirsung’sduct:transpancreaticrouteortransduodenallythroughthepapillaofVater(ERCPWITHORWITHOUTprolongedpancreaticductstenting)Deco
7、mpressingtheproximalpancreaticanddistalbileductsbysphincteroplastytopreventrecurrentpancreatitiswhichcausedbybiliarystone.2021/7/126Externaldrainageofthepancreaticducttodecompressobstructioncausedbystrictureorcalculus(Fig.1)FIGURE12021/7/127Roux-en-Y
8、,side-to-end,pancreaticojejunostomyThecaudal,end-to-end,pancreaticojejunostomyasadrainageprocedureforchronicpancreatitis(FIG2.)FIGURE2.2021/7/128Longitudinaldecompre-ssionofthebodyandtailofthepancreasintoaRouxlimbofjejunum(Fig.3)FIGURE3.2021/7/129Sid
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