黄连解毒汤治疗糖尿病合并颈动脉粥样硬化的临床观察

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1、提要目的：本研究评价黄连解毒汤治疗糖尿病合并颈动脉粥样硬化的临床效果，以期对糖尿病合并颈动脉粥样硬化的临床研究提供进一步的理论依据。方法：将60例糖尿病合并颈部动脉粥样硬化患者随机分为对照组（30例，基础治疗组）和实验组（30例，联合黄连解毒颗粒组），观察两组患者治疗前后血糖、血脂、胰岛素释放试验、颈部动脉形态学改变和血流动力学的变化情况。结果：两组患者治疗后血糖、血脂、胰岛素释放试验、颈总动脉内—中膜厚度、分叉内膜厚度、斑块检出率及颈总动脉、颈内动脉、椎动脉的血流量较治疗前均有明显改善；实验组较比照

2、组改善明显。结论：黄连解毒汤对于改善患者颈动脉粥样硬化有明显临床疗效，优于对照组，且安全性好。关键词颈动脉粥样硬化；糖尿病；黄连解毒汤TheClinicalObservationofHuanglianJieduDecoctioninTheTreatmentofDiabetesCombinedCarotidAtherosclerosisSpeciality：InternalmedicineofTCMAuthor：LiWeishanTutor：Professor.YangWenjunAbstractObj

3、ective:Thisstudyealuateshuanglianjiedudecoctioninthetreatmentofdiabetesmellitusandcarotidatherosclerosisclinicaleffect.Inordertodiabetescombinedwithcarotidatherosclerosisclinicalresearchtoprovidefurthertheoreticalbasis.Methods:60patientswithdiabetesmell

4、itusandcarotidatherosclerosispatientswererandomlydividedintothecontrolgroup(30cases,foundationtreatmentgroup)andthetreatmentgroup(30cases,jointhuanglianjiedudecoction),Intwogroupswereobservedbeforeandaftertreatmentinpatientswithacarotidarterymorphologic

5、alchangesandhemodynamicchanges.Result:Twogroupsofpatientsaftertreatmentofglucose,lipids,insulinreleasetest,carotidarteryintima-mediathicknessofintima-mediathickness,plaque,bifurcationandtheprevalenceofcarotidartery,internalcarotidartery,vertebralarteryb

6、loodflowthanbeforetreatmentwereobviouslyimproved;theexperimentalgroupcomparedwiththecontrolgroupimprovedobviously.Conclusion:HuanglianJieduDecoctioninimprovingpatientswithcervicalatherosclerosishasobviouscurativeeffect,betterthanthecontrolgroup,andthesa

7、fetyisgood.KeywordsCarotidatherosclerosis;Diabetes;Huanglianjiedudecoction目录引言...............................................................................................................................1临床研究...........................................

8、....................................................................................2一、临床资料.......................................................................................................................2（一）病例来源...........