资源描述：
《茵栀黄注射液辅助治疗新生儿高胆红素血症的系统评价》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、茵梔黄注射液辅助治疗新生儿高胆红素血症的系统评价CAJ卜•载PDF下载永久保存本文，请下载至本地黄凤姨黄秋明孝感市中心医院重症医学科孝感市中心医院药学部摘要:目的:系统评价茵梔黄注射液辅助治疗新牛儿高胆红素血症的有效性，为茵梔黄注射液在儿科临床的应用提供循证参考。方法:计算机检索中文科技期刊数据库、中国期刊全文数据库、万方数据库和PubMed等数据库，收集在包含蓝光照射等常规治疗(对照组)基础上联合应用茵梔黄注射液(观察组)治疗新生儿高胆红素血症的随机对照试验，对符合纳入标准的临床研究进行资料提取和质量评价后，进行文献荟萃(Meta)分析。结果:共纳入13篇文献，涉及1864例患儿。
2、Meta分析结果显示，观察组患儿的总有效率(OR二5.70,95%CIM.127.87,P<0.00001)、胆红素降至正常水平所需时间(MD=-2.25,95%CI二-2.98153,P<0.00001)和治疗后胆红素水平(MD=-34.15,95%CI=-47.1021.21,P<0.00001)均明显优于对照组，差异均有统计学意义。结论:茵梔黄注射液联合蓝光照射等常规治疗对新生儿高胆红素血症的效果较好。关键词：茵梔黄注射液;新生儿高胆红素血症;有效性;Meta分析;作者简介:黄凤姨护师。研究方向:临床护理。E-mail:395874225@qq.com作者简介：黄秋明主任药师。
3、研究方向：医院药学。E-mail:2280275098@qq.com收稿日期：2017-07-28SystematicReviewonYinzhihuangInjectioninAdjuvantTreatmentofNeonataiHyperbi1irubinemiaHUANGFengyiHUANGQiumingDept・ofCriticalCareMedicine,XiaoganCentralHospital;Dept,ofPharmacy,XiaoganCentralHospital;Abstract：OBJECTIVE:Tosystematicallyreviewtheeffe
4、ctivenessofYinzhihuanginjectioninacljuvanttreatmentofneonataihyperbilirubinemia,soastoprovideevidence-basedreferenceforitsclinicalapplicationinpediatries.METHODS:Randomizedcontrolledtrialsofconventionaltherapy(controlgroup)includingblue1ightirradiationcombinedwithYinzhihuanginjcction(observatio
5、ngroup)intrcatmentofneonatalhyperbilirubinemiawereretrievedfromChineseScienceandTechnologyPeriodicalFull-textDatabase,ChineseJournalFull-textDatabase,WanfangDatabase,PubMed,etc.Clinicalstudiesmatchedtheinclusioncriteriawereinvolvedtoconductdataextraction,qua!ityevaluationandMetaemalysis.RESULTS
6、:Atotalof13studieswereinvolved,including1864childpatients.ResuItsofMetaanalysisshowedthetotaleffectiverate(OR=5.70,95%CI=4.12-7.87,P<0.00001),requiredtimeforbilirubinlevelreducedtonormal(MD二-2.25,95%CI=~2.98--1.53,P<0.00001)andbilirubinlevelaftertreatment(MD二-34.15,95%CI=-47.10--21.21,P<0.00001
7、)ofobservationgroupweresignificantlybetterthanthoseofthecontrolgroup,withstatisticallysignificantdifferences.CONCLUSIONS:TheefficacyofconventionaltherapyincludingbluelightirradiationcombinedwithYinzhihuanginjectionintreatmentofneo
