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1、硫酸镁在妊娠期高血压轻度子痫前期应用价值doi:10.3969/j.issn.1007-614x.2014.4.7摘要目的:探讨硫酸镁在妊娠期高血压轻度子痫前期中应用的价值。方法:收治轻度子痫前期患者72例,随机分为两组。两组均一般处理,包括保证休息,间断吸氧合理饮食,必要时加地西泮镇静。一组为常规应用硫酸镁。观察指标:发展为重度子痫前期,胎动减少发生率,新生儿1分钟评分,5分钟评分。8例因要求出院,未能继续治疗,退出研究。发展至重度子痫前期的:实验组4/34,对照组3/30,差异无统计学意义(P
2、〉0.05)。胎动减少发生率:实验组62.6%,对照组20%,差异有统计学意义(P0.05)o5分钟评分实验组8.6±0.5分,对照组8.7±0.6分,差异无统计学意义(P〉0.05)。结论:在妊娠期高血压轻度子痫前期中应用硫酸镁的价值较小,意义有待于进一步探讨。关键词轻度子痫前期硫酸镁价值ApplicationvalueofMagnesiumsulfateinmildpreeclampsiainducedbyhypertensionduringpregnancyWangBoDepartmento
3、fgynaecologyandobstetricsofNanyangFirstPeople,sHospitalofHenanProvince,450000AbstractObjective:ToexploreapplicationvalueofMagnesiumsulfateinmildpreeclampsiainducedbyhypertensionduringpregnancy.Methods:Weselected72patientswithmildpreeclampsiaduring2011
4、Januaryto2013January,thesepatientswererandomlydividedintotwogroups.Twogroupsweretreatedwithgeneraltreatment,includingtoensuretherest,intermittentoxygen,reasonablediet,andwithdiazepamsedationifnecessary.AgroupwastreatedwithMagnesiumsulfateregularly.Obs
5、ervationindex:thedevelopmentofseverepreeclampsia,theincidenceoffetalmovementreducing,scoreof1minuteofneonatus,scoreof5minutesofneonatus.8patientswithdrewfromthestudybecauseofdischarge・Thedevelopmenttotheseverepreeclampsia:experimentalgroupwith4/34,con
6、trolgroupwith3/30,therewasnosignificantdifference(P>0.05).Theincidenceoffetalmovementreducing:experimentalgroupwith62.6%,controlgroupwith20%,therewassignificantdifference(P0.05)・Scoreof5minutesofneonatus:Theexperimentalgroupwas8.6+0.5,controlgroup8.7+
7、0.6,andtherewasnosignificantdifference(P>0・05)・Conelusion:TheapplicationvalueofMagnesiumsulfa.teinmildpreeclampsiainducedbyhypertensionduringpregnancyissmal1.TheapplicationvalueoftheMagnesiumsulfateisworthyoffurtherstudy.KeywordsMildpreeclampsia;Magne
8、siumsulfate;Value资料与方法2011年1月-2013年1月收治轻度子痫前期患者72例,年龄20〜39岁,孕周33〜39周,随机分组。入院后完善检查,排除妊娠合并原发高血压及肾脏疾病引起的高血压患者。两组产妇年龄、孕周差异无统计学意义(P>0.05)。参加试验的孕妇均未临产,血压在140〜160/90-llOmmHg,尿蛋白(+),均至少有2次阳性结果。血常规、凝血功能、肝肾功能正常,彩超提示胎儿发育正常,无中枢系统异常表现,无异常临床表现;两组病例在产前均无其他妊娠