酸浆化学成分与质量控制的研究

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1、酸浆化学成分及质量控制研究4．首次对酸浆药材的贮藏条件进行研究，发现环境对酸浆药材内酸浆苦素类成分有明显影响，酸浆苦素类成分对温度、紫外线、霉菌均比较敏感，均可以造成酸浆药材质量下降，所以酸浆药材适宜在避光、通风、常温条件下贮藏。并且酸浆采收后不适宜通过机械烘干或阳光下晾晒，应该使其宿萼和果实分离，通风阴干。5．建立不同采收时间酸浆宿萼及地上部分指纹图谱，测定主要有效成分含量变化。通过有效成分动态变化研究确定宿萼的最佳采收期在8月下旬至9月上旬，而酸浆全草与宿萼的采收时间应有所差异。关键词：酸浆；化学成分；酸浆苦素；质量标准；贮藏辽宁中医药大学201o届硕士学位论文ObjectiveAbstr

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4、leafofphyhalisalkekengiL．var．franchetii(Mast．)Makino．ofsolanaceae．Method：1．Thechemicalconstituentsofcalyxseuandcaulisandleafofphyhalisalkekengi三wereisolatedbysilicagelcolumnchromatographyandsephadexLH-20chromatographytechnique．Onthebasesofphysic—chemicalpropertyandspectroscoieandchemicalevidencethei

5、rs仃uctureswereidentified．2．ThechromatographicfingerprintisestablishedbyHPLC．Thematerialsarecontributeddifferenthabitatandharvestedindifferenttimeanddifferentpartofplantweredetected．Inthemeantime，HPLCiscardedouttodeteminatedthecontentofabovematerials．ResultandConclusion：IBigamountofPhysalinA，Physalin

6、O，PhysalinL，PhysalinB，PhysalinL，luteolin⋯70-p—D—glucopyranosidewereisolatedformthecalysuephysalisthatCanprovidechemicalmarkforhequalitycontr01．Inadditiontenofelevencompoundsalsoisolatedfromtheclaysuephy’saliswereidentifiedonthebasisofphysicsandchemistryconstant，spectralanalysisaswellaschemistrymetho

7、d．Including25，27-dehydro—physalinLwerenewnaturalproducts，and22silaneacidandCuneatasidEwereisolatedfromcalyxphysalisforthefirsttime．2TwelvecompoundwereisolatedfromthestemsandleavesofphyhalisalkekengiL．