合并脑外伤肢体骨折患者血清中vegf、pdgf的含量分析

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1、硕士学位论文中文摘要子关键词骨折，脑外伤，血管内皮生长因子，血小板衍生生长因III硕士学位论文英文摘要ABSTRCTobjectiveToinvestigatethecontentofserumvascularendothelialgrowthfactor(VEGF)andplateletderivedgrowthfactor(PDGF)inthepatientsofsimplefructureandfructurecomplicatedwithTraumaticBrainInjury(Tin)．Toexplor

2、etheacceleratedfactorsoffructurehealinginthefructurecomplicatedwithTBI．AndtoprovideevidenceforclinicalapplicationofVEGFandPDGFtotreatmentwithrefractoryfructure．MethodsChoosing20patientsofsimplefructureand20patientsoffi'ucturecomplicatedwithTBItoVenOUSbloodsam

3、plesinthethirddayandt11ethetenthdayafterfructure．Enzymelinkedimmunosorbentassay(ELISA)wasusedtodetecttheserumlevelofVEGFandPDGFinResult1．Insimplefi-ucturegrouptheserumconcentrationofVEGFinthethirddayandthetenthdayare(77．964-20．05)pg／mland(155．114-25．42)pg／m1．

4、Therearesignificantdefferenceinthethirddayandthetenthday,P<0．05．InsimplefructuregrouptheserumconcentrationofPDGFinthethirddayandthetenthdayare(193．374-51．56)p酌11land(3defferenceinthethirddayand2．InfructurecomplicatedofVEGFinthethirddayandth硕士学位论文英文摘要and(210．6

5、3+24．63)pg／m1．Therearesignificantdefferenceinthethirddayandthetenthday，P<0．05．InfructurecomplicatedwithTBIgrouptheserumconcentrationofPDGFinthethird’dayandthetenthdayare(248．01+94．14)pg／mland(486．20-土：88．09)p∥锄．Alsotherearesignificantdefferenceinthethirddayan

6、dthetenthday，P<0．05．3．Inthem矾daytheserumconcentrationofVEGFinsimplefructureandfructurecomplicatedwithTBIare(77．96+20．05)pg／mland(134．79+20．39)pg／m1．Therearesignificantdefferenceinthetwogroups，P<0．05．InthethirddaytheserumconcentrmionofPDGFinsimplefructureandfr

7、ucturecomplicatedwithTBIare(193．37+51．56)pg／mland(248．01+94．14)pg／m1．Therearesignificantdefferenceinthetwogroups，P

8、esignificantdefferenceinthetwogroups，P<0．05．InthetenthdaytheserumconcentrationofPDGFinsimplefructureandfructurecomplicatedwithTBIare(346．99+92．91)pg／mland(486．20+88．09)p∥1111．Alsothereare