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1、TheNucleusASubjectCollectionfromColdSpringHarborPerspectivesinBiologyArticlesonlineatwww.cshperspectives.orgAllrightsreserved<2011byColdSpringHarborLaboratoryPress,ColdSpringHarbor,NewYorkPrintedintheUnitedStatesofAmericaPublisher
2、ohnInglisAcquisitionEditorRichardSeverProject
3、ManagerMarylizDickersonPermissionsCoordinatorCarolBrownProductionEditorKaarenKockenmeisterCoverDesignerDeniseWeissFrontcoverartwork:Diagramillustratingtheorganizationoftheeukaryoticnucleus.Depictedarechromatin(orange),enclosedbyandanchoredtothenuclearenvelope(gray),andtranscr
4、ibingRNPs(purple),whichafterprocessingareexportedthroughnuclearporecomplexes(greenandblue).(IllustrationcourtesyofMichaelP.Rout.TheRockefellerUniversity.)LibraryofCongressCataloging-in-PublicationDataThenucleus/editedbyTomMistelli,DavidL.Spector,p.cm.Includesbibliographicalre
5、ferencesandindex.ISBN978-0-87969-894-2(hardcover:alk.paper)1.Cellnuclei.I.Mistelli,Tom.II.Spector,DavidL.III.Title.QH595.N852011571,6'6--dc22201003993610987654321AllWorldWideWebaddressesareaccuratetothebestofourknowledgeatthetimeofprinting.Authorizationtophotocopyitemsforinte
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9、tsPreface,ixOVERVIEWTheNucleusIntroduced,1ThoruPedersonTHENUCLEARPER