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1、MolecularNeuropharmacologyAFoundationforClinicalNeuroscienceNOTICEMedicineisanever-changingscience.Asnewresearchandclinicalexperiencebroadenourknowledge,changesintreatmentanddrugtherapyarerequired.Theeditorsandthepublisherofthisworkhavecheckedwithsourcesbelievedto
2、bereliableintheireffortstoprovideinformationthatiscompleteandgenerallyinaccordwiththestandardsacceptedatthetimeofpublication.However,inviewofthepossibilityofhumanerrororchangesinmedicalsciences,neithertheeditors,authors,northepublishernoranyotherpartywhohasbeeninv
3、olvedintheprepa-rationorpublicationofthisworkwarrantsthattheinformationcontainedhereinisineveryrespectaccurateorcomplete,andtheydisclaimallresponsibilityforanyerrorsoromissionsorfortheresultsobtainedfromuseoftheinformationcon-tainedinthiswork.Readersareencouragedt
4、oconfirmtheinformationcontainedhereinwithothersources.Forexampleandinparticular,readersareadvisedtochecktheproductinformationsheetincludedinthepackageofeachdrugtheyplantoadministertobecertainthattheinformationcontainedinthisbookisaccu-rateandthatchangeshavenotbeen
5、madeintherecommendeddoseorinthecontraindicationsforadministration.Thisrecommendationisofparticularimpor-tanceinconnectionwithneworinfrequentlyuseddrugs.MolecularNeuropharmacologyAFoundationforClinicalNeuroscienceSECONDEDITIONEricJ.Nestler,MD,PhDNashFamilyProfessor
6、ofNeuroscienceChairman,DepartmentofNeuroscienceandDirectoroftheMountSinaiBrainInstituteMountSinaiSchoolofMedicineNewYork,NewYorkStevenE.Hyman,MDProfessorofNeurobiologyHarvardMedicalSchoolProvostHarvardUniversityCambridge,MassachusettsRobertC.Malenka,MD,PhDNancyFri
7、endPritzkerProfessorofPsychiatryandBehavioralSciencesDirector,NancyFriendPritzkerLaboratoryStanfordUniversitySchoolofMedicinePaloAlto,CaliforniaNewYorkChicagoSanFranciscoLisbonLondonMadridMexicoCityMilanNewDelhiSanJuanSeoulSingaporeSydneyTorontoCopyright©2009bythe
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