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1、细胞生物学期中试卷(2003-11-22)姓名∶专业∶一二三四五六总分一、填空题(每空0.5分，共5分)1.决定红细胞ABO血型的物质是糖脂，它由脂肪酸和寡糖素链组成。A型血糖脂上的寡糖链较O型多一个；B型血仅多一个。2.根据题意,将与A、B、C、D相对应的词用连线连起来:Cellscommunicateinwaysthatareanalogoustohumancommunication.Decidewhichofthefollowingformsofhumancommunicationareanalogoustoautocrine,paracr
2、ine,endocrine,andsynapticsignalingbycells.A.Atelephoneconversation:autocrineB.Talkingtopeopleatacocktailparty:endocrineC.Aradioannouncement:synapticsignalingD.Talkingtoyourself:paracrine3.Whatisthemajorfactorthatdeterminesthelimitofresolutionofalightmicroscope?4.编码载脂蛋白B的基因在肠组
3、织中转录成mRNA后,第2153位的C被形成U,使CAA密码转变成终止密码UAA,使翻译提前终止。5.是细胞外基质的受体蛋白。在结构上，它们是异二聚体，。这种跨膜蛋白的细胞外部分有一个球形的头部，可与细胞外基质蛋白结合，而细胞质结构域则可与相结合。二、判断以下各题是否正确,若正确,用T表示,不正确用F表示,并做简要说明。(每题1分，共10分)1.BoththeGTP-boundasubunitsandnucleotide-freeb¡complexes,butnotGDP-bound,fullyassembledGproteins,activat
4、eothermoleculesdownstreamofG-protein-linkedreceptors.11答:2.Thedensityofwaterislessthanthedensityofice.答:3.Waterhasahighspecificheat.答:4.Thereisnofundamentaldistinctionbetweensignalingmoleculesthatbindtocell-surfacereceptorsandthosethatbindtointracellularreceptors.答:5.Howisitt
5、hatdifferentcellscanrespondindifferentwaystoexactlythesamesignalingmoleculeevenwhentheyhaveidenticalreceptors?答:6.ProteinkinaseAitselfisdifferentindifferentcelltypes,whichexplainswhytheeffectsofcyclicAMPvarydependingonthetargetcell.答:7.Itisthoughtthatextracellularligandbindin
6、gtoareceptortyrosinekinaseactivatestheintracellularcatalyticdomainbypropagatingaconformationalchangeacrossthelipidbilayerthroughthesingletransmembraneahelix.答:8.Atrialnatriureticpeptides(心钠肽)bindtoareceptorthatactivatesaGprotein,whichinturnactivatesguanylylcyclase(鸟苷环化酶)topro
7、ducecyclicGMPwhichthenactivatesacyclicGMP-dependentproteinkinase(PKG).答:9.Becauseprokaryoticcellshaveneithermitochondrianorchloroplasts,theycannotcarryouteitherATPsynthesisorphotosynthesis.答:10．电镜的波长与电压有关，电压越高，波长越短，分辨率越高。答:三、选择题(请将正确答案的代号填入括号，每题1分，共20分)111.Whichoneofthefollow
8、ingisincorrectforthebiogenesisofeukaryoticribosomes?()a.25-50%ofthep
