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1、玉屏风散对变应性鼻炎外周血清中NO的影响和相关性研究摘要:目的观察玉屏风散对变应性鼻炎(AR)患者血清一氧化氮(N0)含量的影响及其免疫相关性。方法选取我院2015年1月〜12月门诊收治的30例肺气虚型AR患者为试验组,予玉屏风散口服治疗1个月,以症状、体征和血清N0水平为评判指标,并与我院体检中心健康体检者30例健康对照组进行比较。结果试验组血清中N0水平明显高于对照组,差??有统计学意义(P0.05);30例试验组均未发生不良反应。结论血清NO参与了AR患者的免疫发病过程,它可以为AR的诊断和治疗提供参考依据;玉屏风散能阻断N0的免疫作用
2、,改善AR患者的临床表现,且无毒副作用。关键词:变应性鼻炎;N0;免疫相关性StudyontheEffectofYupingWindPowderonNOinPeripheralSerumofAllergicRhinitisZHANGGuo-qingl,CHENYu1,YEHuo-quan2,TANGYue-yingl,ZENGYi-shengl,XUYa~hual(1.E.N.T.Department,TheSecondPeople,sHospitalAffiliatedtoFujianUniversityofTraditionalChine
3、seMedicine,Fuzhou350003,Fujian,China;2.DepartmentofClinicalLaboratory,TheSecondPeople,sHospitalAffiliatedtoFujianUniversityofTraditionalChineseMedicine,Fuzhou350003,Fujian,China)Abstract:ObjectiveToobservetheeffectsofYupingfcngSanonthebloodserumNocontentofAllergicRhinitis(A
4、R)patients,alongwithitsimmunecorrelation.MethodsCollect30casesofpatientswithLungQiDeficiencytypeofARwhowereundergoingtreatmentinourhospitalclinicbetweenJanuary2015andDecember2015asatreatmentgroupinthisexperiment,alongwith30casesofhealthypersonsadmittedinMedicalexaminationce
5、nterofourhospitalasacontrolgroup.ThetreatmentgrouptookYupingfengSanorallyforonemonthwhilethecontrolgroupwasnotgivenanyintervention.Takingsymptom,signandserumNolevelasevaluationindexs,comparetwogroupsofdata.ResultsTheserumNolevelofthetreatmentgroupwasevidentlyhigherthanthato
6、fthecontrolgroupbeforetheexperiment,andtherewasstatisticalsignificanceexistedinthedate(P0.05)whentwogroupsofdatawerecomparedwitheachotheragain.Therewasnoadversereactionsinthetreatmentgroupsduringtherapy,inaddition.ConclusionSerumNowhichisinvolvedintheImmunopathologicalproce
7、sshaveprovidedareferencebasisforthefuturediagnosisandtreatmentofAR.Furthermore,italsosucessfullyprovedthatYupingfengSanisabletointerrupttheeffectsofNoinimmuneresponse,improvingclinicalsymptomswithoutanypoisonoussideeffects.Keywords:Allergicrhinitis;NO;Immunecorrelation应性鼻炎(
8、AllergicRhinitis,简称AR),祖国医学属于〃鼻軌〃范畴。NO是新近发现的一类重要信使分子,已经被证实其参与气管、血管平滑肌的调节和神经递质的传递,细