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1、XX大学毕业论文麻黄汤对正常小鼠肛温的影响2014年6月25日麻黄汤对正常小鼠肛温的影响作者：刘国清，贺丰，莫志贤，余林中，罗佳波【关键词】麻黄汤；，，发汗；，，热贮；，，肛温；，，调定点摘要：目的：观察麻黄汤对正常小鼠肛温的影响。方法：将120只小鼠分成两组：麻黄汤9g/kg组(以单味麻黄计)、空白对照组，每组60只，分别于给药后0,5,10,15,20,25,30min测量小鼠肛温，计算出肛温的变化值。结果：麻黄汤9g/kg组和空H对照组两组肛温在5,20,25min时没有显著性差异(P0.05),在10,15
2、min时麻黄汤组高于空白对照组(P0.001),在30minUj*间点麻黄汤组低于空白对照组(P0.005)。从麻黄汤组内来看，10min与5min比较有显著性差异(P0.05),15min与10min比较有显著性差异(P0.001),20min与15min比较有显著性差异(P0.001),25min与20min比较无显著性差异(P0.05),30min与25min比较无显著性差异(P0.05)。即麻黄汤组小鼠肛温从5min开始有升高的趋势，从10min开始上升，到15min升至最高点，与其他5个时间点均有显著性差
3、异(P0.001)；20min时开始下降，到30min时低于空白对照组。结论：麻黄汤对止常小鼠肛温的作用在5〜15min之间有一个体温上升期，以增加体内热贮，之后随着出汗，体温下降。麻黄汤对正常动物体温调定点的影响，还需要深入研究。关键词：麻黄汤；发汗；热贮；肛温；调定点EffectsofMahuangtangonAnalTemperatureinNormalMiceAbstract:Objective:ToobservetheeffectofMahuangtang(MHT)onanaltemperatureinn
4、ormalmice.Methods:120miceweredivivedintotwogroups:MHT9g/kgdosagegroup(countedbysingleMahuang)andcontrolgroup.Therewere60miceineverygroup.Theanaltemperaturewasmeasuredat0minutes,5minutesJOminutesJ5minutes,20minutes,25minutesand30minutesafteradministrationofMHTT
5、hechangeoftheanaltemperaturewascalculated.Results:TheanaltemperaturebetweenMHT9g/kgdosagegroupandcontrolgrouphadnosignificantldifferenceafter5minutes,after20minutesand25minutes.ButtheanaltemperatureofMHTgroupwashigherthanthatofcontrolgroupafter10minutesand15mi
6、nutesjowerafter30minutes.InsidetheMHTgroup,thereweredifferencesignificantlybetweenafter10minutesand15minutes(P0.05),betweenafter15minutesandafter10minutes(P0-001),betweenafter20minutesandafter15minutes(P0.001).TherewerenosignificarUldifferencebetweenafter25min
7、utesandafter20minutes(P0.05),betweenafter30minutesand25minutes(P0.05).Inotherwords,theanaltemperatureofMHTgrouphadanascendingtrendafter5minutes,begantoriseafter10minutes5arrivedatthehighestpointafter15minutes,whichhadsignificantdifferencewithotherfivetimepoint
8、s(P0.001),begantodescendafter20minutes,andafter30minuteswaslowerthanthatofcontrolgroup.Conclusion:Thereareatemperatureascendperiodafter5minutesto15minutesintheprocessoftheeffectsof
