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时间:2018-11-29
《曲美他嗪联合阿托伐他汀治疗冠心病的疗效及对血脂的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、曲美他嗪联合阿托伐他汀治疗冠心病的疗效及对血脂的影响【摘要】目的研究分析�R床上使用曲美他嗪联合阿托伐他汀治疗冠心病、降低血脂的效果。方法180例冠心病患者,随机分为对照组和观察组,各90例。对照组患者给予曲美他嗪治疗,观察组患者在对照组的基础上联合使用阿托伐他汀治疗。治疗后比较两组患者的总有效率、血脂指标以及心功能。结果①治疗后,观察组患者治疗总有效率为92.2%,显著高于对照组的82.2%,差异具有统计学意义(P<0.05)。②观察组患者血清中总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)较对照组显著降低,高密度脂蛋白胆固醇(HD
2、L-C)较对照组显著升高,差异均具有统计学意义(P<0.05)。③心功能:观察组患者左心室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)明显低于对照组,左心室射血分数(LVEF)明显高于对照组,差异均具有统计学意义(P<0.05)。结论曲美他嗪联合阿托伐他汀治疗冠心病疗效确切,优于曲美他嗪单独治疗,具有改善患者心功能、降低血脂的双重效果,临床上值得广泛推广。中国6/vie 【关键词】曲美他嗪;阿托伐他汀;冠心病;降血脂 DOI:10.14163/j.ki.11-5547/r.2017.07.056 Curativeeffectbytrim
3、etazidinebinedentofcoronaryheartdiseaseanditsinfluenceonbloodlipidLUXiao-yan.ShandongDezhouCityQiheCountyPeople’sHospital,Dezhou251100,China 【Abstract】ObjectiveToresearchandanalyzeeffectbytrimetazidinebinedentofcoronaryheartdiseaseandbloodlipiddecreasing.MethodsAtotalof180patient
4、slydividedintocontrolgroupandobservationgroup,etazidinefortreatment,andtheobservationgroupreceivedadditionalatorvastatintotrimetazidineinthecontrolgroupforbinedtreatment.parisonadeontotaleffectiverate,bloodlipidindexesandcardiacfunctionbetent.Results①Aftertreatment,theobservationg
5、rouphadobviouslyhighertotaleffectiverateintreatmentas92.2%than82.2%inthecontrolgroup,andtheirdifferencehadstatisticalsignificance(P<0.05).②Theobservationgrouphadmuchlototalcholesterol(TC),triglyceride(TG),loension(LVEDD),leftventricularendsystolicdiameter(LVESD)andhigherleftventri
6、cularejectionfraction(LVEF)thanthecontrolgroup,andtheirdifferencesallhadstatisticalsignificance(P<0.05).Conclusionbinationoftrimetazidineandatorvastatinintreatingcoronaryheartdiseaseprovidespreciselycurativeeffect,entbytrimetazidine.Thismethodshoprovingcardiacfunctionanddecreasing
7、bloodlipid,anditisotion. 【Keyetazidine;Atorvastatin;Coronaryheartdisease;Bloodlipiddecreasing
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