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时间:2018-11-20
《掺钕钇铝石榴石激光对小鼠移植瘤转移的影响论文》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、掺钕钇铝石榴石激光对小鼠移植瘤转移的影响论文.freel-2,照射后第8日观察肿瘤的生长及肺转移情况.结果不同方式激光照射组的肿瘤肺转移程度明显低于对照组(P0.01),封闭照射组肿瘤生长慢于对照组(P0.01).结论不同方式的Nd-YAG激光治疗可减少小鼠肿瘤肺转移,提示Nd-YAG激光除体腔应用外.freelouse;neoplasmmetastasisAbstract:AIMTostudytheeffectsofdifferentmannersofirradiationofNd-YAGlaseronmetastasisoftransplantedt
2、u-morinmice.METHODSNiy-ninemiceannersofNd-YAGlaser-2.Ontheeighthday,metastasisofthetransplantedtumortothelungetastasisoftrans-plantedtumorinmiceinthreelasergroupsshoorinsealingirradiationgroupgreorMetastasisinmicecanbeinducedbydifferentmannersofirradiationofNd-YAGlaser.Itsuggests
3、thatNd-YAGlasercanbeusedinen-doscope,decreasingthepossibilityoftumormetastasisinbinationium-yttriumalu-minumgar,Nd-YAG),波长1.06μm,是近红外激光,可经石英光导纤维传输,水和血红蛋白对其吸收较少,作用较深,是体腔肿瘤治疗中较为理想的激光光源[1],已较广泛用于体表及体腔肿瘤的治疗[2,3].在恶性肿瘤的临床治疗中,尽管治疗手段不断完善,但仍有不少患者死于肿瘤转移.如何在治疗中抑制肿瘤转移,提高疗效,是人们关注的问题之一.其他种类激光
4、对淋巴回流及肿瘤转移影响的结论不一[4,5].我们用不同的Nd-YAG激光照射方式治疗小鼠移植瘤,比较其治疗效果及对肿瘤转移的影响.1材料和方法1.1光源系统武汉产Nd-YAG激光器,输出功率0~70E,A,LeonardPF.Anesthesiaforneo-dymium-YAG(Nd-YAG)laserresectionofmajorairors[J].Anesthesiology,1984;60(3):230-232.[2]PonecRJ,KimmeyMB.Endoscopictherapyofesophagealcan-cer[J].SurgCl
5、inNorthAm,1997;77(5):1197-1217.[3]GardnerA,HesteredicineInstitute,Acade-myofMedicalSciencesofChina.Experimentalstudyonim-plantableprosquamouscellcarcinomaofstomachofmouse[J].ZhonghuaZhongliuZazhi(ChinJOncol),1980;2(3):161-163.[7]GaoJ,QianSS,LiBG.Experimentalstudyonmetastasisoftu-
6、mourtreatedbyHpDbinetolaser[J].ZhonghuaZhongliuZazhi(ChinJOncol),1986;8(4):256-258.[8]LeiJY.Metastasisofmalignanttumour[J].GuomermannI,SternJ,FrankF.InterceptionoflyphaticdrainagebyNd:YAGlaserirradiationinraturinarybladder[J].LasersSurgMed,1984;4(2):167-172.[10]ShanghaiNeoplasmHo
7、spital.Zhongliudefangzhi(Thepreven-tionoftumour)[M].2nded.Shanghai:ShanghaiKexueJishuChubanshe(ShanghaiTechnologyPublishingHouse),1997:65.
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