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1、TrendsinHealthcareInvestmentsandExits2018InvestmentsandFundraisingReachAll-TimeHighs,FocusGrowsonEarly-StageM&AANNUALREPORT2018Follow@SVB_FinancialEngage#SVBHealthcare2TableofContents2017KeyHighlightsHealthcareInvestmentsandFundraisingHealthcareBigExitM&AandIPOs2018OutlookGlossaryAbouttheAuthors3521
2、313233TrendsinHealthcareInvestmentsandExits201832017KeyHighlights:InvestmentsHealthcareInvestmentsandFundraisingSetRecordsin2017•U.S.healthcareventurefundraisingsetarecord,reaching$9.1B–a26percentincreaseover2016–andsurpassingthe2015recordof$7.5B.•Investmentsintoventure-backedbiopharma,medicaldevice
3、anddiagnosticsandtools(Dx/Tools)companiesarealsoexpectedtobreakarecordin2017,increasing31percentover2016toreach$15.5B.•SpikesinQ1andQ4biopharmaSeriesAdealspropelledthesectortoanotherrecordyear,posting$2.8Bininvestments.•Biopharmainvestmentcenteredononcologyandplatformcompanies.Platformcompaniespique
4、dinvestorinterest,astheirtechnologiesshowedpromiseformultipleexitsacrossdifferentindications.•Non-invasivemonitoring,especiallyincardiovascular,uro/gynandneuro,tookoffinmedicaldeviceSeriesAinvestments.•Neuroinvestmentsurgedin2017,withsignificantinterestfromnicheinvestorsandincubators.•Artificialinte
5、lligencespurredtechinvestorinterestinDx/Tools,leadingtorecordinvestment.•Liquidbiopsyinvestmentexploded,punctuatedby$1.8BininvestmentsintoGuardantHealth,GRAILandHumanLongevity.TrendsinHealthcareInvestmentsandExits201842017KeyHighlights:ExitsBiopharmaandDeviceM&AsFocusedonEarly-StageCompanies•Biophar
6、masawawaveofIPOs,beating2016’stotal,whilebigexitM&Aactivityslowed.IPOshadasignificantupswinginpre-moneyvaluations.•OncologydealsledM&AactivityanddominatedIPOs,accountingfor36percentofallexitsin2017.•BiopharmaM&Acontinuedtofocusonearly-stagecompanies,whileIPOsshiftedtolaterstage.•Crossoverinvestorssc
7、aledbacktheirbiopharmainvestmentsfrom2015butcontinuetodrivetheirexistingportfoliocompaniestoIPO.•DeviceM&Aactivitycontinuedatasteadypace,withafocusonminimallyinvasivedevicesandnext-genvisualization/im
