初诊支气管哮喘患者呼出气no水平与血清il-17的相关性研究

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1、授予单位代码10089学号或申请号20153131中国图书分类号R562.2+5HebeiMedicalUniversity硕士学位论文专业学位初诊支气管哮喘患者呼出气NO水平与血清IL-17的相关性研究研究生：葛志胜导师：杨红申教授专业：内科学二级学院：第二医院2018年3月目录中文摘要···········································································································1英文摘要····

2、······································································································3英文缩写··········································································································5研究论文初诊支气管哮喘患者呼出气NO水平与血清IL-17的相关性研究前言···········

3、····························································································6材料与方法························································································6结果········································································

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6、·························28综述白介素17在哮喘疾病中的作用·····················································31致谢·············································································································43个人简历··············································

7、·······················································44中文摘要初诊支气管哮喘患者呼出气NO水平与血清IL-17的相关性研究摘要目的：检测不同水平FeNO哮喘患者血清IL-17浓度变化，探讨两种气道炎症标志物与肺功能损伤、肥胖相关性，评价IL-17、FeNO在支气管哮喘分型中的作用。方法：随机选择2016年3月-2017年5月于河北省二院收治的初诊哮喘患者66例，分FeNO低、中、高值三组。除检测患者FeNO水平外，记录血清IL-17浓度、肺功能、体重指数。同

8、期选体检者12例为健康对照组。结果：1.哮喘组血清IL-17浓度高于对照组（P<0.05）；高值组血清IL-17浓度高于对照组（P<0.05）。2.哮喘三组间比较，中值组血清IL-17浓度高于高值组（P<0.05）；余组间比较无明显差异（P>0.05）。3.哮喘高值组FEV1/pred明显大于中值组（P<0.05），余组间比较无明显差异（P>0