【持续性肾脏替代治疗crrt英文精品课件】pediatric crrt terminology

【持续性肾脏替代治疗crrt英文精品课件】pediatric crrt terminology

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时间:2018-10-11

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1、PediatricCRRTTerminologyHelenCurrierBSN,RN,CNNAssistantDirector,Renal/PheresisTexasChildren’sHospitalHouston,TexasHistoryofContinuousRenalReplacementTherapy(CRRT)1960Continuousarteriovenousapproachfirstdescribedfortreatmentofrenalfailure1974Ultrafiltrationisolatedfromhemodialysiscircuitan

2、dtheadditionofahemofilter1975Hemofiltrationtechniqueproposed1979-82SCUFandCAVHusedbyPaganini(MD)andWhitman(RN)atClevelandClinicHistoryofContinuousRenalReplacementTherapy(CRRT)1980sCRRTusedinpediatrics1987Pump-assistedCRRTintroduced1990CRRTconsideredstateofthearttherapyfortreatmentofacuter

3、enalfailure1993StandardsofClinicalPracticeforCRRTpublishedbytheAmericanNephrologyNurses’Association(ANNA)andendorsedbytheAmericanAssociationofCriticalCareNurses(AACN)HistoryofContinuousRenalReplacementTherapy(CRRT)2000ContinueddevelopmentofintegratedbloodpumpandfluidbalanceequipmentforCRR

4、T2002SecondpCRRTmeetinginOrlando,FL2004ThirdpCRRTmeetinginOrlando,FLTestyourknowledgePediatricCRRTtherapiesareapproximatelyA.40yearsoldB.30yearsoldC.20yearsoldD.10yearsoldTestyourknowledgePediatricCRRTtherapiesareapproximatelyA.40yearsoldB.30yearsoldC.20yearsoldD.10yearsoldIndicationsforC

5、RRTintheCriticalCareSettingFluidremovalSoluteremovalBasicConceptsofCRRT:ConceptsRelatedtoFluidRemovalorUltrafiltrationBloodflowArteriovenousVenovenousHydrostaticpressureArteriovenousVenovenousOtherfactorsHematocritPlasmaproteinsTransmembranepressureBasicConceptsofCRRT:ConceptsRelatedtoSol

6、uteRemovalorClearanceConvection–solutedrag;hemofiltrationDiffusion–concentrationgradient;hemodiafiltrationSoluteMassTransferinCRRTPost-DilutionCVVHCVVHDPre-DilutionCVVHCVVHDFQbQbQbQbQeffQeffQeffQeffQdQdQrQrQrSoluteMolecularWeight andClearanceSolute(MW)SievingCoefficientDiffusionCoefficien

7、tUrea(60)1.01±0.051.01±0.07Creatinine(113)1.00±0.091.01±0.06UricAcid(168)1.01±0.040.97±0.04*Vancomycin(1448)0.84±0.100.74±0.04***P<0.05vssievingcoefficient **P<0.01vssievingcoefficientComparisonofUreaClearance:CVVHvsCVVHD(Maxvoldetal,CritCaremed.2000Apr;28(4):1161-5

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