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时间:2018-10-11
《【持续性肾脏替代治疗crrt英文精品课件】pediatric crrt terminology》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、PediatricCRRTTerminologyHelenCurrierBSN,RN,CNNAssistantDirector,Renal/PheresisTexasChildren’sHospitalHouston,TexasHistoryofContinuousRenalReplacementTherapy(CRRT)1960Continuousarteriovenousapproachfirstdescribedfortreatmentofrenalfailure1974Ultrafiltrationisolatedfromhemodialysiscircuitan
2、dtheadditionofahemofilter1975Hemofiltrationtechniqueproposed1979-82SCUFandCAVHusedbyPaganini(MD)andWhitman(RN)atClevelandClinicHistoryofContinuousRenalReplacementTherapy(CRRT)1980sCRRTusedinpediatrics1987Pump-assistedCRRTintroduced1990CRRTconsideredstateofthearttherapyfortreatmentofacuter
3、enalfailure1993StandardsofClinicalPracticeforCRRTpublishedbytheAmericanNephrologyNurses’Association(ANNA)andendorsedbytheAmericanAssociationofCriticalCareNurses(AACN)HistoryofContinuousRenalReplacementTherapy(CRRT)2000ContinueddevelopmentofintegratedbloodpumpandfluidbalanceequipmentforCRR
4、T2002SecondpCRRTmeetinginOrlando,FL2004ThirdpCRRTmeetinginOrlando,FLTestyourknowledgePediatricCRRTtherapiesareapproximatelyA.40yearsoldB.30yearsoldC.20yearsoldD.10yearsoldTestyourknowledgePediatricCRRTtherapiesareapproximatelyA.40yearsoldB.30yearsoldC.20yearsoldD.10yearsoldIndicationsforC
5、RRTintheCriticalCareSettingFluidremovalSoluteremovalBasicConceptsofCRRT:ConceptsRelatedtoFluidRemovalorUltrafiltrationBloodflowArteriovenousVenovenousHydrostaticpressureArteriovenousVenovenousOtherfactorsHematocritPlasmaproteinsTransmembranepressureBasicConceptsofCRRT:ConceptsRelatedtoSol
6、uteRemovalorClearanceConvection–solutedrag;hemofiltrationDiffusion–concentrationgradient;hemodiafiltrationSoluteMassTransferinCRRTPost-DilutionCVVHCVVHDPre-DilutionCVVHCVVHDFQbQbQbQbQeffQeffQeffQeffQdQdQrQrQrSoluteMolecularWeightandClearanceSolute(MW)SievingCoefficientDiffusionCoefficien
7、tUrea(60)1.01±0.051.01±0.07Creatinine(113)1.00±0.091.01±0.06UricAcid(168)1.01±0.040.97±0.04*Vancomycin(1448)0.84±0.100.74±0.04***P<0.05vssievingcoefficient**P<0.01vssievingcoefficientComparisonofUreaClearance:CVVHvsCVVHD(Maxvoldetal,CritCaremed.2000Apr;28(4):1161-5
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