131碘治疗甲状腺功能亢进并发房颤临床效果观察

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1、131碘治疗甲状腺功能亢进并发房颤临床效果观察王晓燕，纪建松，朱丽萍，徐丽珍，蔡杰［摘要］目的：分析131碘治疗甲状腺功能亢进并发房颤的临床效果。方法：收集我院2012年1月-2013年12月期间诊治的甲状腺功能亢进并发房颤患者89例作为研究对象，以随机数字表分组的方式分为试验组(45例)与对照组(44例)，对照组患者采用常规抗甲状腺药物他巴唑治疗，试验组采用131碘治疗，对两组患者的整体治疗效果、T3、T4、心率改善情况、不良反应发生率进行分析对比。结果：研究结果显示，试验组患者的整体治疗效果明显高于对照组(P<0.0

2、5)，T3、T4、心率改善情况明显优于对照组(P<0.05),不良反应发生率明显低于对照组(P<0.05)。结论：131碘治疗甲状腺功能亢进并发房颤具有良好的临床疗效，能有效提高患者的整体治疗效果，促进T3、T4、心率改善，降低不良反应发生率，值得在临床应用上推广。［关键词］131碘甲状腺功能亢进房颤临床效果D0l:10.3760/cma.j.issn.0376-2491.2015.16.005作者单位：王晓燕，纪建松，朱丽萍，323000,浙江省丽水市，浙江省丽水市中心医院；325035,浙江省温州市，温州医科大

3、学附属第五医院TheClinicalEffectof131IodineintheTreatmentofThyroidFunctionHyperfunctionComplicatedwithAtrialFibrillationWangXiaoyan,JiJiansong,ZhuLiping,XuLizhen,CaiJieAbstract:ObjectiveToanalyzeoftheclinicaleffectof131iodinetreatmentinthyroidfunctionhyperfunctionwithatrial

4、fibrillation.Methods89casesofthyroidfunctionhyperthyroidismcomplicatedwithatrialfibrillationfromJanuary2012toDecember2013werecollectedastheresearchobjectandweredividedintotheexperimentalgroup(45cases)andthecontrolgroup(44cases).Thecontrolgroupweretreatedbyroutineant

5、i-thyroiddrugs-methimazoletreatmentwhilethetreatmentgroupweretreatedwith131iodine.Theoveralltreatmenteffectofthepatientsinthetwogroups,theirT3,T4index,improvedheartratesandtheincidenceofadversereactionswerecompared.ResultsTheresultsshowedthattheoveralltherapeuticeff

6、ectoftheexperimentalgrouppatientswasobviouslyhigherthanthatofcontrolgroup(P<0.05);T3,T4andimproveheartrateintheexperimentalgroupweresignificantlybetterthanthatofcontrolgroup(P<0.05);theincidenceofadversereactionsintheexperimentalgroupwasobviouslylowerthantheco

7、ntrolgroup(P<0.05).Conclusion131iodineiseffectiveinthetreatmentofthyroidfunctionhyperfunctioncomplicatedwithatrialfibrillation.Itcaneffectivelyimprovethepatients’overalltreatmenteffect,promotetheT3,T4andheartrate,andreducetheincidenceofadversereactions,whic

8、hisworthpopularizationinclinicalapplication.Keywords:131iodine;thyroidfunctionhyperfunction;atrialfibrillation;clinicaleffect甲状腺功能亢进并发房颤是甲