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ID:19868717
大小:17.06 MB
页数:54页
时间:2018-10-07
《细胞连接与细胞粘连》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、第七章细胞连接与细胞粘连Celljunctionandcelladhesion第一节细胞连接celljunction1、封闭连接Occludingjunction2、锚定连接Anchoringjunctions3、通讯连接Communicationjunctions第二节细胞粘附分子celladhesionmolecule1、Occludingjunction(tightjunctions)2、Anchoringjunctions(1)Actinfilamentattachmentsitesa.Cell-celladherensjunctions(adhesionbelts)b.
2、Cell-matrixadherensjunction(focalcontacts)(2)Intermediatefilamentattachmentsites.a.Cell-cell(desmosomes)b.Cell-matrix(hemidesmosomes)3、Communicationjunctions(1)Gapjunctions(2)ChemicalsynapsesThreetypesofCellJunctions:闭锁连接(occludingjunction):紧密连接(tightjunction)TheTightJunctionFormsBarrierAcros
3、sCellsDespitethemanystructuralandbiochemicaldifferenceamongvarioustypesofepithelia,allhavethefunctionofbeingselectivelypermeabletofluidsoneachside.TheTightjunctionplaytwodistinctrolesinthisselectivebarrierfunction.Preventtheapicalmembraneproteinsfrommovingtobasolateralsurface.Sealthespacesbet
4、weenepithelialcellstopreventsothatmoleculescannotmovebetweencells.desmosome电镜下显示细胞间连接——桥粒通讯连接(communicatingjunction):是细胞间的一种连接通道,除了使细胞间相互连接外,还介导细胞通讯,包括:(1)间隙连接(gapjunction);(三)化学突触(chemicalsynapse):由突触前膜、突出间隙和突触后膜组成,信息的传递需要有传递物(如神经递质)Legend:Whenanactionpotentialreachesanerveterminal,itopensvo
5、ltage-gatedCa2+channelsintheplasmamembrane,allowingCa2+toflowintotheterminal.TheincreasedCa2+inthenerveterminalstimulatesthesynapticvesiclestofusewiththeplasmamembrane,releasingtheirneurotransmitterintothesynapticcleft
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