高血压英文ppt精品课件hypertension diabetes a dangerous

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1、HYPERTENSION&DIABETES:“ADANGEROUSDUO”ThomasD.Giles,M.D.LouisianaStateUniversityMedicalSchoolNewOrleans,LouisianaMETABOLICSYNDROMEDIABETES&HYPERTENSIONThomasD.Giles,M.D.LouisianaStateUniversityMedicalSchoolNewOrleans,LouisianaDatafromKingHetal.DiabetesCare.19

2、98;21:1414-1431.TopThreeCountriesforDiabetesCVMortalityRiskDoubleswithEach20/10mmHgBPIncrement**Individualsaged40-69years,startingatBP115/75mmHg.CV,cardiovascular;SBP,systolicbloodpressure;DBP,diastolicbloodpressureLewingtonS,etal.Lancet.2002;60:1903-1913.JNC

3、VII.JAMA.2003.CVmortalityriskSBP/DBP(mmHg)012345678115/75135/85155/95175/105AssociationofSBPandCVMortalityinMenWithType2Diabetes250200150100500<120120-139140-159160-179180-199SBP(mmHg)CVmortalityrate/10,000person-yrNondiabeticDiabeticCV,cardiovascular;S

4、BP,systolicbloodpressure.StamlerJetal.DiabetesCare.1993;16:434-444.≥200EndPointHazardRatiosAssociatedWithIncreaseinSBPHazardratioAdlerAetal.BMJ.2000;321:412–419.UpdatedmeanSBP(mmHg)00.51.01.52.02.53.03.54.0110120130140150160170Anyendpointrelatedtodiabetes(P<0

5、.0001)Deathrelatedtodiabetes(P<0.0001)All-causemortality(P<0.0001)CharacteristicsofAdults20YearsWithPreviouslyDiagnosedDiabetesCharacterisiticSaydahSHetal.JAMA.2004;291:335-342.MeanbodymassindexObese(%)HypertensionTakingantihypertensivemedicationHypercholeste

6、rolemiaTakinglipid-controllingmedicationNHANESIII29.941.654.877.044.927.7NHANES1999-200032.354.651.485.254.556.1P.002.008.32.05.02<.001SaydahSHetal.JAMA.2004;291:335-342.PercentageofAdultsWithRecommendedLevelsofVascularDiseaseRiskFactorsinNHANESIIIandNHANES199

7、9-2000NHANESIII(n=1204)NHANES1999-2000(n=370)6050403020100Adults(%)HbA1cLevel<7%BP<130/80mmHgTotalCholesterolLevel<200mg/dL(5.18mmol/L)VascularDiseaseRiskFactorsMetabolicSyndrome:NCEP/ATPIIIDefinitionPresenceofatleast3of5riskfactors:AbdominalobesityElevatedblo

8、odpressureElevatedfastingglucoseElevatedtriglyceridesLowHDL-CThirdReportoftheNationalCholesterolEducationProgramExpertPanel.ExecutiveSummary;May2001.NIH#01-3670.NoData<10%10%-14%15