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1、PorcineandRangiferineBrucellosis:BrucellasuisEnzooticAbortion,ContagiousAbortion,UndulantFeverOverviewOrganismHistoryEpidemiologyTransmissionDiseaseinHumansDiseaseinAnimalsPreventionandControlActionstoTakeCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012TheOrganismTheOrganismBr
2、ucellasuisGramnegativecoccobacillusFacultativeintracellularpathogenFivebiovars1,2,3:pigs4:reindeerandcaribou5:rodentsCanpersistintheenvironmentCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012TheManyNamesofBrucellosisHumanDiseaseMaltaFeverUndulantFeverMediterraneanFeverRockFe
3、verofGibraltarGastricFeverAnimalDiseaseBang’sDiseaseEnzooticAbortionEpizooticAbortionSlinkingofCalvesRamEpididymitisContagiousAbortionCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012HistoryHistoryofBrucellosisEarly1800sSirWilliamBurnettdifferentiatesfeversaffectingseamenintheMe
4、diterraneanLate1880sSirDavidBruceisolatesthecauseofMaltafever,MicrococcusmelitensisDr.BernhardBanddiscoverscauseofcattleabortioninDenmark,Bacteriumabortus(“Bang’sdisease”)CenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012HistoryofBrucellasuis1914:B.suisfirstrecognized1972:Nationa
5、lBrucellosisEradicationProgramB.suisnoweliminatedfromcommercialswineherdsinU.S.FeralswineanemergingreservoirCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012EpidemiologyGeographicDistributionWorldwideinswine-raisingregionsEradicatedfromdomesticpigsU.S.,UnitedKingdom,Canada,Europ
6、eOccursinferalswineinmanyareasSporadicoutbreaksSouthandCentralAmericaAsiaAfricaCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012GeographicDistributionBiovars1and3WorldwideBiovar2WildboarinEuropeBiovar4(rangiferinebrucellosis)ArcticregionsofN.America,RussiaBiovar5(murinebrucellos
7、is)FormerUSSRCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012GeographicDistributionCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012IntheUnitedStatesCenterforFoodSecurityandPublicHealth,IowaStateUniversity,2012PopulationsatRiskOc