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1、122例卵巢早衰患者中医证候分析及致病因素调查 【摘要】：目的探讨卵巢早衰中医证候及分布规律、卵巢早衰发病原因与中医证候的关系。方法对122例卵巢早衰患者进行病情、病因调查及中医辨证。结果卵巢早衰中医症状临床呈多样趋势。122例卵巢早衰患者中,肝郁肾虚证33.61%,肝肾阴虚证18.03%,脾肾阳虚证15.57%,热盛伤津证15.57%,肾虚血瘀证8.20%,肝郁脾虚证7.38%。在68.03%卵巢早衰患者病史中可找到现代生活环境及生活方式因素对疾病发生的影响。因情致因素致病者占31.15%,因药物、疾病因素致病者占31.97
2、%；因情志及药物、疾病双重因素致病者占4.92%。因情志因素致病组,以肝郁肾虚证比例最高(P<0.05)；因药物、疾病因素致病组,以热盛伤津证、肝郁肾虚证所占比例较高(P<0.05)；无诱因致病组37例,以肝肾阴虚、肝郁肾虚、脾肾阳虚三证为主,3组比较,P>0.05。结论肝郁肾虚、肝肾阴虚、脾肾阳虚、热盛伤津为卵巢早衰常见证候；除患者个体先天禀赋不足、肾气未盛、冲任气血不充或由遗传因素致卵巢早衰外,现代生活环境及生活方式因素对卵巢早衰发病有促进作用。【关键词】卵巢早衰 中医证候 病因 Abstract：Ob
3、jectiveToexploretheTCMsyndromeanditsdistributionregularityofprematureovarianfailure(POF)aswellastherelationbetweentheetiologicalfactorandTCMsyndromeofit.MethodsThepathogeneticconditionandetiologicalfactorof122patientswithPOFweresurveyed,andTCMsyndromedifferentiation
4、wascarriedoutonthem.ResultsTheTCMsymptomsofPOFmanifestedthetendencyofvariety.Amongthe122cases,Gan-stagnationandShen-deficiencytypeaccountedfor33.61%ofthem,Gan-Shenyindeficiencytypefor18.03%,Pi-Shenyangdeficiencytypefor15.57%,Jindamageduetoexcessiveheattypefor15.57%,
5、Shen-deficiencybloodstasistypefor8.20%,andGan-stagnationandPi-deficiencytypefor7.38%.Theinfluenceofmodernlivingenvironmentandlifestyletothediseasewasfoundin68.03%ofthepatients’casehistory.31.15%ofthepatientswasinducedbyemotion,31.97%bydrugsanddisease,and4.92%bybotho
6、fthem.Inpatientsinducedbyemotion,theproportionofGan-stagnationandShen-deficiencytypewasthehighestascomparedwiththeothertypes(P<0.05).Inpatientsinducedbydrugsanddisease,comparedwiththeother4types,JindamageduetoexcessiveheattypeaswellasGan-stagnationandShen-deficie
7、ncytypewerehigher(P<0.05).In37patientswithoutobviousetiologicalfactor,Gan-Shenyindeficiencytype,Gan-stagnationandShen-deficiencytypeaswellasPi-Shenyangdeficiencytypewerethemost,butnosignificantdifferencewasshownamongthem(P>0.05).ConclusionGan-stagnationandShen
8、-deficiency5type,Gan-Shenyindeficiency,Pi-ShenyangdeficiencytypeandJindamageduetoexcessiveheatarethecommonlyencounteredsyndromesinpatients
