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ID:19757642
大小:2.45 MB
页数:44页
时间:2018-10-05
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1、PulmonaryHypertensionPulmonaryModuleStevenW.HarrisMHS,PA-CPulmonaryHypertensionDefinedaspressurewithinthepulmonaryarterialsystemelevatedabovethenormalrange.greaterthan25mmHgatrestor30mmHgwithexercisePulmonaryarterialpressure(PAP)usually12-15mmHgLeftatrialpressure6-10mmHg7/5/20212P
2、ulmonaryhypertensiondevelopswhenfloworresistancetoflowacrossthepulmonaryvascularbedincreasesFourCategoriesofPulmonaryHypertensionPulmonaryhypertensionfromdisordersoftherespiratorysystemorhypoxemia.Pulmonaryvenoushypertension.Pulmonaryhypertensionfromchronicthromboembolicdisease.Pu
3、lmonaryarterialhypertension.(PAH)7/5/20213ChronicpulmonaryhypertensionisanimportantcauseofrightventricularfailureintheUnitedStates.Manyoftheindividualswhodieeachyearofchronicobstructivepulmonarydisease(COPD)succumbsecondarilytorightventricularfailureresultingfrompulmonaryhypertens
4、ion.7/5/20214Inaddition,greaterthan200,000deathsoccuryearlyfromacutepulmonaryembolism,themostcommoncauseofsudden-onsetpulmonaryhypertensionandacuterightventricularfailure.7/5/202157/5/202167/5/202177/5/20218Inpersonsmorethan50yearsofage,Corpulmonaletheconsequenceofuntreatedpulmona
5、ryhypertension,isthethirdmostcommoncardiacdisorder(aftercoronaryandhypertensiveheartdisease).7/5/20219EntitiesthatcauseincreasedpulmonarybloodflowCongenitalHeartDiseaseLefttorightshunt“Hyperkinetic"pulmonaryhypertensioncanbeseeninpatientswithcongenitalheartdiseasewhohaveextensivel
6、eft-to-rightcardiacshuntsthatproducealargepulmonarybloodflowIncreasedcardiacoutputstatessevereanemias7/5/202110EntitiesthatcauseanincreasedresistancetoflowPulmonaryembolismInsitupulmonaryembolismPulmonaryfibrosisSarcoidosis,scleroderma,orextensivepulmonaryresectionSevereCOPDThorac
7、icdeformitiesLargetumororinfiltrate7/5/202111EntitiesthatcausechangesinarteriolesHypoxia(altitude)COPDHypoventilation(sleepapnea)AcidosisDrugsPulmonaryarterialhypertension(PAH)7/5/202112Entitiesthatcausevenouspressurechanges&vascularresistanceLeftatrialhypertension=MitralStenosisL
8、eftventricularfailurePulmonaryven
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