（黑色素瘤）课件

《（黑色素瘤）课件》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、MelanomaXiezheContentCaseandquestionsIntroductionTypesRiskfactorsDiagnosisTreatementAccordingtothepatient’swife,thisskinlesionhasbeenpresentforthepastseveralmonths,andshebelievesthatithasincreasedinsizeandbecomedarkerduringthistime.Thepatientisotherwisehealthy.CaseDuringaroutinephysical

2、examinationofa30-year-oldman,youdiscovera1.5-cm,pigmentedskinlesionontheposterioraspectofhisleftshoulder.Thislesionisnonindurated,hasill-definedborders,andiswithoutsurroundingerythema.Examinationofthepatient’sleftaxillaandneckrevealsnoidentifiableabnormalities.Nootherpigmentedskinlesion

3、sareobservedduringyourthoroughphysicalexamination.QuestionsWhatisthemostlikelydiagnosis?Whatisyournextstep?Whatisthebesttreatmentforthisproblem?IntroductionMelanomaisamalignanttumorofmelanocyteswhicharefoundpredominantlyinskinbutalsointhebowelandtheeye.Itisoneofthelesscommontypesofskinc

4、ancerbutcausesthemajority(75%)ofskincancerrelateddeathsTypesSuperficialspreadingNodularsclerosisLentigomalignaAcrallentiginousGeneticFairskin(2.1)Redhair(3)Caucasian(5-10)Morethan20nevionbody(3.4)Bluseyes(4.5)Easilyburnedandunabletotan(4.5)Familialcases(4-10)Priorhistoryofmelanoma(900)R

5、iskFactorsEnvironmentalFactorsSunlightAreasneartheequatorFirstsunburnatyoungageOthersAgeGenderHighersocioeconomicclassHalogenatedcompoundsSymptomsApopularmethodforrememberingthesignsandsymptomsofmelanomaisthemnemonic“":Diagnosissymmetricalskinlesion.nlargingorlevation:Enlargingorelevati

6、ngiameter:molesgreaterthan6 mmaremorelikelytobemelanomasthansmallermoles.orderofthelesionisirregular.BADCEEolor:melanomasusuallyhavemultiplecolors.DiagnosisBiopsyExcisionalskinbiopsySmallpunchbiopsyTreatementSurgeryCompletesurgicalexcisionradicallymphnodedissectionAdjuvanttreatmentayear

7、ofhigh-doseinterferontreatmentChemotherapyandimmunotherapydacarbazine(DTIC)interleukin-2(IL-2)orinterferon(IFN)QuestionsWhatisthemostlikelydiagnosis?Whatisyournextstep?Whatisthebesttreatmentforthisproblem?Thankyouforyourattention!