精品ppt课件pediatric influenza disease lessons learned from a recent

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1、PediatricInfluenzaDisease:LessonsLearnedFromaRecentPandemicMarthaL.Muller,MDAssistantProfessor,DepartmentofPediatricsUniversityofNewMexicoHealthSciencesCenterTalkObjectivesTodiscussepidemiologyofseasonaland2009H1N1influenzainpediatricsNationwideUniversi

2、tyofNewMexicoChildren’sMedicalCenterTodiscussclinicalmanifestationsofseasonaland2009H1N1influenzadiseaseinpediatricsTodiscusstherelevanceofbacterialco-infectionsinpediatricpatientswithinfluenzadiseaseTodiscussthedifficultiesweencounteredwithtreatmentand

3、preventionofdiseaseinourpopulationPurposeSowhybotherwithcontinuedsurveillance?PerCDCFluactivity,causedbyeither2009H1N1orseasonalfluviruses,mayriseandfall,butitisexpectedtocontinueforseveralmoremonths.http://www.cdc.gov/h1n1flu/Further,animalstudieshaves

4、uggestedthat2009H1N1virusesaremorepathogenicthanseasonalH1N1virusesAnnSaudiMed2010;30:1-10PediatricInfluenzaEpidemiologySignificantpediatricrespiratoryvirusGreatestmorbidityandhospitalizationratesinyoungeragesCommunityepidemicsaresustainedbyhighinfectio

5、nratesinpreschoolandschool-agedchildrenPediatric2009H1N1EpidemiologyInitialcasesinUnitedStatesnotedinchildren15thand17thApril2009noted2childreninCaliforniatohaveinfectionNumberoflaboratory-confirmedinfluenza-associatedhospitalizationsandcumulativehospit

6、alizationratesper10,000population,byagegroupandsurveillanceweek---EmergingInfectionsProgram(EIP)andnewsites,*2006--07,2007--08,2008--09,†and2009--10§U.S.influenzaseasons.http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5902a3.htmCDC:http://www.cdc.gov/flu/wee

7、kly/Moreimportantinfluenza‘stats’intheworldofpediatricsEpidemiologythattranslatesdirectlyintotheclinicalforum:Secondaryhouseholdattackratesthoughttobeapproximately27.3%Inschoolsettings,infectedchildrenpredictedtoinfect2.4otherchildrenChildrenmaybecontag

8、iouslongerAnnSaudiMed2010;30:1-10ClinicalmanifestationsInfluenzaillnessinpediatricsInfant/toddlerversuschild≥5yearsoldTraditionalsymptomsAcuteotitismediaBronchiolitisLaryngotracheobronchitisEncephalopathyClinicalmanifestationsInf