皮肤结构和功能双语课件

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1、Theconstructionsandfunctionsofskin皮肤结构和功能Prof.DanqiDeng(邓丹琪教授、博导）Dept.ofDermatology,theSecondAffiliatedHospitalofKunmingMedicalUniversityhttp：//sy.ynderma.com.cnHealthybodydependonhealthskin.Theskinisaaesthetic（审美）organ.Theskinisavitalorganlikeheartis.OutlineEpidermis表皮Dermis真皮Subcutaneoust

2、issue皮下组织Cutaneousappendage皮肤附属器Thefunctionsofskin皮肤的功能Theskinanatomy(皮肤的解剖)Itisthelargestorganofthebody,makingup16%ofbodyweight,withasurfaceof1.5m2Thedepthofskinis0.5～4mm.Theepidermis(表皮）is0.04-1.6mm，theaveragedepthofepidermisis0.1mm.Thedermis（真皮）is1-3mm.TheskinanatomyIt’scontinuouswiththe

3、digestivesystem(lips).腔口部位形成皮肤黏膜的移行区Theskingrooves(皮沟)andskinridges(皮嵴)Therearethreestructurallayerstotheskin:theepidermis（表皮）,thedermis（真皮）andsubcutis（皮下组织）Thedermiscontainsnerveendings,sweatglands（汗腺）andoilglands,hairfollicles（毛囊）,andbloodvessels（血管）.ThecolorofskinTypeITypeIITypeIIITypeIV

4、TypeVTypeVIThetypeofskinTheepidermis(表皮)Theepidermisisanepithelium（上皮）comprisedofkeratinocytes（角质形成细胞）anddendriticcells(langerhanscells朗格汉斯细胞,merkelcells麦克尔细胞,melanocytes黑素细胞).Themaincellsoftheepidermisarethekeratinocytes(角质形成细胞80%),whichsynthesisetheproteinkeratin(角蛋白).stratumbasale,基底层str

5、atumcorneum角质层stratumspinosum棘层stratumgranulosum颗粒层stratumlucidum透明层Theepidermis(表皮)Stratumbasale(基底层)：isamajorregionofmitotic(分裂)activity.Thebasallayeriscomposedofcolumnar（柱状）cellswhichareanchoredtoabasementmembrane（基地膜）Epidermaltransittime(表皮通过时间或更替时间):Newkeratinocytesslowlymigrateuptowar

6、dthesurfaceoftheepidermis.Theprocessneeds28days.Fromstratumbasaletostratumgranulosumis14days,thentostratumcorneumandgraduallyshedis14days.Totalis28days.Stratumspinosum(棘细胞层)iscomposedof4to8layersofprickle(多角形的）keratinocytes.Keratinocytesareattachedtoeachotherbyintercellularbridge（细胞间桥）,whic

7、haredesmosomes（桥粒）Stratumgranulosum(颗粒层)Locatedtheupperofstratumspinosum.Stratumgranulosumiscomposedof1to3layersofratherflattened(扁平)cells.Therearesomelargeandbasophil（嗜碱性）granule,calledkeratohylinegranules(透明角质颗粒）incytoplasm(细胞浆）.ratherflattenedcellscon