非酒精性脂肪性肝病中医证型与血清生化指标的相关性研究硕士学位论文

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1、广西中医学院硕士学位论文非酒精性脂肪性肝病中医证型与血清生化指标的相关性研究研究生：导师：院系（部所）：瑞康临床医学院专业：中医内科学研究方向：肝脏疾病的中西医结合防治完成日期：目录中文摘要················································1英文摘要················································3引言·················································6正文····································

2、·············71文献研究················································72临床研究···············································172.1临床资料·············································172.2研究方法·············································213结果···················································234

3、讨论···················································275存在的问题和展望·······································31结论················································33参考文献···············································34附录················································37综述·······················

4、·························39致谢················································48攻读学位期间发表的学术论文目录···························48作者声明···············································50个人简历···············································51主要缩略词英文缩写英文全称中文名称NAFLDnonalcoholicfattyliverdisease非酒精性脂肪性

5、肝病NAFLnonalcoholicsimplefattyliver非酒精性脂肪肝NASHnonalcoholicsteatohepatitis非酒精性脂肪性肝炎IRinsulinresistance胰岛素抵抗ALTalanineaminotransferase丙氨酸氨基转移酶ASTaspartateaminotransferase天冬氨酸氨基转移酶GGTgamma-glutamyltranspeptidase谷氨酰转移酶ALPalkalinephosphatase碱性磷酸酶TGtriglyceride甘油三酯TCtotalcholesterol总胆固醇HDLhigh

6、-densitylipoprpteincholesterol高密度脂蛋白LDLlow-densitylipoprpteincholesterol低密度脂蛋白FPGfastingplasmaglucose空腹血糖中文摘要目的：研究非酒精性脂肪性肝病（NAFLD）患者中医证型与实验室常用血清生化指标之间的关系，为中医辨证分型提供客观依据，为中西医结合防治NAFLD提供理论依据。方法：采用横断面研究方法，对自2010年10月至2011年3月广西中医学院附属瑞康医院体检中心体检者中及肝胆内科就诊者中，符合入组条件的150例NAFLD患者进行中医辨证分型，并记录其实验室常用血清

7、生化指标，应用统计学分析方法处理所获得的信息与资料。结果：(1)150例患者平均年龄44.46岁，中位数44.50岁，40～50岁者最多（43.33%），男女比例为1.94:1；(2)肝郁脾虚证为NAFLD最常见证型（39.33%），男女患者均多属肝郁脾虚证；(3)B超检查150例患者多为轻度弥漫性脂肪肝（56.66%）；(4)ALT肝郁脾虚证与其余证型有极显著性差异（P<0.01），肝郁脾虚证检测结果在正常参考值范围，其余证型检测结果高于正常参考值上限，其中肝肾不足者升高最高，痰浊壅阻者升高最低，肝肾不足>痰瘀互结>湿热内蕴>痰浊壅阻；AST各证型