资源描述：
《type of manuscript case report：手稿的案件类型报告》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、Typeofmanuscript:CasereportCognitiveimpairmentandepilepsyseizurecausedbyhypoparathyroidism:acasereportandreviewofliteratureMarinaTitlic1,AnteTonkic2,IvanaJukic2,PetarFilipovic-Grcic1,KresimirKolic3¹DepartmentofNeurology,SplitUniversityHospital,Split,Croatia²DepartmentofInternalmedic
2、ine,SplitUniversityHospital,Split,Croatia³DepartmentofRadiology,SplitUniversityHospital,Split,CroatiaAuthor'saddress:MarinaTitlic,MDPhDDeparmentofNeurology,SplitUniversityHospitalSpinciceva1,Split21000CROATIATel.:0038521556426Fax.:0038521556675email:marina.titlic@gmail.comAbstractWe
3、reporta46-year-oldmanwithidiopathichypoparathyroidismwhopresentedwithgraduallyprogradingcognitiveimpairmentandgeneralisedtonicclonicepilepsy.Computedtomography(CT)andmagneticresonanceimaging(MRI)ofbrainshowedcalcificationinthebasalganglia,thalamusandcerebralwhitematter.Calciumlevelw
4、aslowandphosphorwasincreasedinserum,butparathormonlevelwaslow.Followingintroductionofreplacementtherapy,cognitivefunctionsimprovedaswell.AftertreatmentwithcalciumandvitaminDsupplementationheshowedclinical,cognitiveimpairmentandlaboratorialimprovements.Keywords:hypoparathyroidism,cog
5、nitiveimpairment,CT,MRI,calcium,phosphor.BackgroundHypoparathyroidismcanresultfromlackordecreasedsecretionofparathormon(PTH)orfromdefectiveresponsivenessofeffectororganstoPTH.Neurologicalsignsofhypoparathyroidismincludesymptomaticorlatenttetany,seizures,hemiparesis,difficultyinspeak
6、ing,ischemicattacks,incaseofbasalgangliaandcerebellarcalcificationsalsochoreoatetosis,parkinsonismandcerebellarsyndrome(1-3).Clinical,laboratoryandradiologicalfeaturesofcasesofhypoparathyroidismmakebasisofdiagnosticsoftheprimarydiseasewithvariousneurologicalsigns.Laboratoryfindingsr
7、evealedseverehypocalcemiaandhyperphosphatemia,andserumlowlevelsofparathyroidhormone.Computedtomography(CT)andmagneticresonanceimaging(MRI)ofbrainshowedcalcificationsinthebasalganglia,thalamus,cerebralwhitematterandcerebellum(4-7).Wereportaveryrarecaseofapatientwithhypoparatiroidismw
8、homanifestedcogniti
