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1、读书报告会2017Differentiationoflarge(≥5cm)gastrointestinalstromaltumorsfrombenignsubepithelialtumorsinthestomachCONTENTS目录1Introduction2Materialsandmethods3Results4Discussion5Case6ConclusionPage3Case患者：女性，61岁主诉：发现左上腹肿块5年专科体查：腹部平软，全腹无压痛及腹肌紧张，剑突下偏右可触及一肿块，大小约4×6cm,边缘清楚，无压痛。CasePage4Page5CasePage6Case免疫组化结果显
2、示:Bcl-2(++),CD34(+++),Calretinin(－),EMA(±),Ki-67(+约0.9%),S-100(－),SMA(－),CD117(+++),DOG-1(+++),CD99(++)间质瘤Page7IntroductionLikemanyotherorgans,thestomachisnotonlytheoriginofepithelialtumorsandlymphomas,butalsoawiderangeofmesenchymaltumors.Approximately3%ofallgastrictumorsbelongtothelattergroup.Gastr
3、icmesenchymaltumorscanbedividedintofourmaincategories;truesmoothmuscletumorsneurogenictumors,fibroblastictumors,andgas-trointestinalstromaltumors(GISTs).Gastricmesenchymaltumorstypicallymanifestasasub-epitheliallesiononbothimagingandpathologicexam-inations.Exceptinveryrareleiomyosarcomas,allgastricm
4、esenchymaltumorsotherthanGISTsarealmostalwaysbenign.GISTs,ontheotherhand,evenwhentheyaresmall,arepotentiallymalignant.Therefore,accuratedifferentiationofGISTsfromotherbenignsubepithelialtumorsiscrucialforplanningmanagementoptionsPage8IntroductionIntroductionInthisstudy,weattemptedtodeterminewhethert
5、herearecharacteristicCTfeatureswhichmayhelpdifferentiateGISTsfromnon-GISTsinpatientswithlarge(≥5cm)gastricsub-epithelialtumors.Additionally,weassessedwhetherradio-logists’performanceindifferentiationcanbeimprovedwithknowledgeoftheseCTcriteria.Page9Page101Patients2CTacquisition3Imageanalysis4Statisti
6、calanalysisMaterialsandmethodsMaterialsandmethodsFinally,120patientswith≥5cmgastricsubepithelialtumorswereenrolledinourstudy:99patientswithGIST(57men,42women;meanage,60.4±12.9(standarddeviation(SD))years;range,25–85years),16patientswithsch-wannoma(7men,9women;meanage,58.9±12.4(SD)years;range,37–83ye
7、ars),and5patientswithleiomyoma(3men,2women;meanage,42.4±13.2(SD)years;range,27–63years).Page11ResultsPage12Clinicalandpathologicfeaturesof120patientswithlarge(≥5cm)gastricsubepithelialtumors.ResultsPa
