compatibility testing：兼容性测试

《compatibility testing：兼容性测试》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、CompatibilityTestingAhmadShihadaSilmiMsc,FIBMSIUGWhatiscompatibilitytesting?AlsocalledpretransfusiontestingPurpose:ToselectbloodcomponentsthatwillnotcauseharmtotherecipientandwillhaveacceptablesurvivalwhentransfusedIfproperlyperformed,compatibilitytestswillconfirmABOcompatibilitybetwee

2、nthecomponentandtherecipientandwilldetectthemostclinicallysignificantunexpectedantibodiesCompatibilitytesting?ThereareseveralcomponentsofcompatibilitytestingProperspecimencollectionReviewingpatienttransfusionhistoryABO,Rh,andantibodytesting(screen/ID)CrossmatchingActualtransfusionCompa

3、tibilitytestingCanbedividedinto3categories:PreanalyticalproceduresSerologicaltestingPostanalyticalproceduresPre-analyticalphasesPatientidentificationSpecimencollectionReviewofpatienthistoryPatientIdentificationMustconfirmrecipient’sIDfrombraceletONthepatientFullpatientnameandhospitalnu

4、mberNameofphysicianhttp://www.usatoday.com/tech/news/techinnovations/2006-07-17-chips-everywhere_x.htmSampleIdentificationThesampleshouldalsohavethefullpatientname,hospitalnumber,andphysicianDateandtimeofcollection,phlebotomist’sinitialsAllofthisshouldbeontherequestformandthesampleSpec

5、imenTubesPinkTop-EDTARedTop–noadditivesSpecimenCollectionCollectedintubewithEDTAornoadditivesIfthevenipuncturecauseshemolysis,thesamplemayberejectedTruehemolysisinthepatientistheresultofcomplementactivationSamplesarelabeledatthebedside(pre-labelingisnotrecommended)Arecordofindividualsw

6、hocollect(ortest)thespecimensshouldbedocumentedinorderto“backtrack”incaseofanerrorSpecimenCollectionIfthesampleisdrawnfromanIVline,theIVinfusionshouldbestopped5-10minutespriortoblooddrawingandthefirst10mLdiscardedTestingshouldbeperformedonsampleslessthan72hoursorelsecomplementdependent

7、antibodiesmaybemissed(complementcanbecomeunstable)GettingthehistoryLookatrecipient’srecordsforanypriorunexpectedantibodiesPrevioustransfusionreactionsSerologicalTesting3tests:ABO/RhAntibodydetection/identificationCrossmatchABO/RhTypingIntheABOtyping,theforwardandreverseMUSTmatchInthe