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1、降调后血清雌激素水平预测IVF结局的价值?5l0?四川医学2011年4月第32卷(第4期)SichuanMedicalJournal,2011,Vo1.32,No.4降调后血清雌激素水平预测IVF结局的价值周瑞年,王雪梅(成都市妇女儿童中心医院生殖医学中心,四川成都610091)论着【摘要】目的探讨在ⅣF助孕过程中,对垂体进行降调节后,基础血清雌激素的水平对预测IVF妊娠结局的意义.方法回顾分析202例临床周期,均采用黄体中期长方案对垂体进行降调节,按降调后启动日基础血清雌激素水平分为3组,分别为E2<
2、15pg/ml,15pg/ml<E2~<30pg/ml,30pg/ml<E2≤50prnl,探讨启动日基础血清雌激素水平对助孕结局的预测价值.结果15pg/ml<E2~30pg/ml组用药量及Gn天数最少,获卵数最多,另两组患者的用药量较多,获卵数相对较少,3组患者在Gn用量,获卵数,妊娠率及周期取消率方面均没有显着性差异.结论启动日患者15pg/ml<E2~<30pg/ml将会有低的用药量和较多的获卵数,单独以启动日E2这个指标,预测卵巢不良反应的发生及妊娠结局,尚不能说
3、明问题,应结合更多因素进行分析预测.【关键词】血清雌激素;卵巢不良反应;妊娠【中图分类号】R321.2【文献标识码】A【文章编号】1004-0501(2011)04-0510-03EvaluationofthepredictivevalueforIVFoutcomesofserulnestrogenlevelafterdownregulation.ZHOURui—nian,WANGXue—mei.ChengduWomen&ChildrensMedicalCenterReproductiveMedica
4、lCenter,Chengdu,Sichuan610091,China【Abstract】ObjectiveToinvestigatethepredictiverelevanceforpregnancyoutcomesofbasalserumestrogenlevelsafterpituitarydownregulationduringin-vitrofertilization(IVF)procedures.MethodsToreviewtotal202IVF—ETcycles,whichweredownre
5、gulatedbylongprotocolatmidlutealphase,wereretrospectivelyanalyzedandweredividedinto3groupsaccordingtothebasalserumestrogenlevelsonfirstdayofovarianhyper?stimulation,i.e.E2<15pg/,~group,15pg/~<E2≤30pg/mlgroup.and30pg/ml<E2~50pg/mlgroup.Thepredictive
6、valueofbasalserumestrogenlevelsonfirstdayofovarianhyper-stimu-lationforIVFoutcomeswasanalyzed.ResultsGonadotropinconsumptionanddaysofovarianstimulationweretheleastandsum—bersofoocyteobtainedwerethemostin15pg/ml<E2~30pgc(mlgroup,thedrugconsumptionintheoth
7、er2groupswererelative-lymoreandnumbersofooeyteobtainedwererelativelyless.Therewerenosignificantdifferencesingonadotropindoses,numbersofoocyteobtained,pregnancyrateandcyclecancellationratebetweenallthreegroups.ConclusionPatientsinthegroupwith15pg/ml<E2<
8、;~30pg/mlonthefirstdayofovarianhyper—stimulationwereassociatedwitlllessgonadotropinconsumptionandmoreoocytesobtained,butthesinglemeasurementofE2onthefirstdayofovarianhyper—stimulationisnotsufficientfor
